(3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione

Base Information

Chemical Name:(3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione
CAS No.:67106-24-5
Molecular Formula:C6H10N2O3
Molecular Weight:158.15500
Hs Code.:
DSSTox Substance ID:DTXSID60514193
Nikkaji Number:J1.903.052K
Wikidata:Q82374373
Mol file:67106-24-5.mol

Synonyms:67106-24-5;(3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione;DTXSID60514193

Suppliers and Price of (3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione

Chemical Property:

PSA：85.41000
LogP:-1.46640
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:158.06914219
Heavy Atom Count:11
Complexity:192

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1C(=O)NCC(=O)N1)O
Isomeric SMILES:C[C@H]([C@H]1C(=O)NCC(=O)N1)O

Technology Process of (3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione

There total 2 articles about (3S)-3-(1-Hydroxyethyl)piperazine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 686-44-2,73464-89-8,73464-90-1,76970-35-9
L-Thr-Gly

: 67106-24-5
(S)-3-(1-Hydroxy-ethyl)-piperazine-2,5-dione

Guidance literature:: With Zr₆-based UiO-66 metal-organic frameworks; at 80 ℃; for 24h;
DOI:10.1021/acscatal.1c01782

Reference yield: 58.0%

: 67864-88-4
methyl (2S,3R)-2-(2-{[(tert-butoxy)carbonyl]amino}acetamido)-3-hydroxybutanoate

: 67106-24-5
(S)-3-(1-Hydroxy-ethyl)-piperazine-2,5-dione

Guidance literature:: With hydrogenchloride; In methanol; for 1h; Ambient temperature;

Reference yield:

: 67106-24-5
(S)-3-(1-Hydroxy-ethyl)-piperazine-2,5-dione

: 85724-77-2
Acetic acid 1-((S)-5-benzyl-5-methoxy-3,6-dioxo-piperazin-2-yl)-ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 75 percent / 12 h / Heating

2: 75 percent / potassium t-butoxide / dimethylformamide / 12 h

3: 95 percent / 6M-HCl / ethanol / 2.5 h / Ambient temperature

4: NBS / 0.5 h

5: 81 percent / hydrogen, triethylamine, methanol / 10percent Pd-C / 1 h

With hydrogenchloride; methanol; N-Bromosuccinimide; potassium tert-butylate; hydrogen; triethylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;