6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol

Base Information

Chemical Name:6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol
CAS No.:128887-74-1
Molecular Formula:C15H23 N O2
Molecular Weight:249.3486
Hs Code.:
DSSTox Substance ID:DTXSID50926226
Mol file:128887-74-1.mol

Synonyms:128887-74-1;6-(2,4-dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol;BRN 4294217;1-alpha,3-alpha-Dimethyl-6-beta-(2,4-dimethylphenyl)-3,4-beta-piperidinediol;3,4-Piperidinediol, 1,3-dimethyl-6-(2,4-dimethylphenyl)-, (1-alpha,3-alpha,4-beta,6-beta)-;6-(2,4-DIMETHYLPHENYL)-1,3-DIMETHYL-PIPERIDINE-3,4-DIOL;DTXSID50926226;BXHUHAQDRAWEPJ-UHFFFAOYSA-N;LS-115157

Suppliers and Price of 6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol

Chemical Property:

Vapor Pressure:7.45E-07mmHg at 25°C
Boiling Point:392.2°Cat760mmHg
Flash Point:191°C
PSA：43.70000
Density:1.1g/cm³
LogP:1.72980
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:249.172878976
Heavy Atom Count:18
Complexity:296

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C2CC(C(CN2C)(C)O)O)C

Technology Process of 6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol

There total 2 articles about 6-(2,4-Dimethylphenyl)-1,3-dimethylpiperidine-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 120729-71-7
(2R,5R)-2-(2,4-Dimethyl-phenyl)-5-hydroxy-1,5-dimethyl-piperidin-4-one

: 128887-74-1
(3R,4R,6R)-6-(2,4-Dimethyl-phenyl)-1,3-dimethyl-piperidine-3,4-diol

Guidance literature:: With sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1007/BF00766856

Reference yield:

: 120729-69-3
(E)-3-(2,4-Dimethyl-phenyl)-1-(2-methyl-oxiranyl)-propenone

: 128887-74-1
(3R,4R,6R)-6-(2,4-Dimethyl-phenyl)-1,3-dimethyl-piperidine-3,4-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / propan-2-ol / 20 °C

2: 80 percent / NaBH₄ / propan-2-ol

With sodium tetrahydroborate; In isopropyl alcohol;
DOI:10.1007/BF00766856