Proteinase K

Base Information

• Chemical Name: Proteinase K
• CAS No.: 39450-01-6
• Molecular Formula: C29H27N2O12P
• Molecular Weight: 626.504641
• Hs Code.: 35079090
• Mol file: 39450-01-6.mol

Synonyms:E.C.3.4.21.64;Endopeptidase K;Prok;Protease K;Proteinase,Tritirachium album serine;Tritirachium albumproteinase K;

Chemical Property of Proteinase K

Chemical Property:

• Appearance/Colour: Light brown powder
• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: 2-8°C
• Solubility.: H2O: 10 mg/mL, slightly hazy, brown-yellow
• Water Solubility.: Miscible with water.

Purity/Quality:

99%, ^*data from raw suppliers

Proteinase K Solution 20mg/ml ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: Xn
• Statements: 36/37/38-42
• Safety Statements: 23-24-26-36/37-22-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: A stable and highly reactive serine protease; used for protein and nucleic acid isolation.Proteinase K is used in the purification of RNA and DNA from tissues or cell lines. It finds application in protein modification, determination of enzyme localization and inactivation of RNases/DNases during nucleic acid extraction. It is also used in mitochondria isolation and removal of endotoxins bound to cationic proteins like lysozyme and ribonuclease A. Further, it is involved in the treatment of paraffin embedded tissue sections in order to expose antigen binding sites for antibody labeling. Useful for the proteolytic inactivation of nucleases during the isolation of DNA and RNA.Removes endotoxins that bind to cationic proteins such as lysozyme and ribonuclease A.Reported useful for the isolation of hepatic, yeast, and mung bean mitochondriaDetermination of enzyme localization on membranesTreatment of paraffin embedded tissue sections to expose antigen binding sites for antibody labeling.Digestion of proteins from brain tissue samples for prions in Transmissible Spongiform Encephalopathies (TSE) research.