Thieno[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-2-[[[2-[4-(dimethylamino)phenyl]-2-oxoethyl] methylamino]methyl]-4,7-dihydro-7-methyl-4-oxo-

Base Information

• Chemical Name: Thieno[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-2-[[[2-[4-(dimethylamino)phenyl]-2-oxoethyl] methylamino]methyl]-4,7-dihydro-7-methyl-4-oxo-
• CAS No.: 672326-32-8
• Molecular Formula: C28H29ClN4O3S
• Molecular Weight: 537.082

Synonyms:

Chemical Property of Thieno[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-2-[[[2-[4-(dimethylamino)phenyl]-2-oxoethyl] methylamino]methyl]-4,7-dihydro-7-methyl-4-oxo-

Chemical Property:

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Technology Process of Thieno[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-2-[[[2-[4-(dimethylamino)phenyl]-2-oxoethyl] methylamino]methyl]-4,7-dihydro-7-methyl-4-oxo-

There total 1 articles about Thieno[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-2-[[[2-[4-(dimethylamino)phenyl]-2-oxoethyl] methylamino]methyl]-4,7-dihydro-7-methyl-4-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-chlorobenzyl)-7-methyl-2-((methylamino)methyl)-4-oxo-4,7-dihydrothieno[2,3-b]-pyridine-5-carboxamide (672326-30-6) + 2-bromo-1-(4-(dimethylamino)phenyl)ethanone (37904-72-6) → N-(4-chlorobenzyl)-2-(((2-(4-(dimethylamino)phenyl)-2-oxoethyl)(methyl)amino)methyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide (672326-32-8)

Guidance literature:

With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 24h;

Reference yield:

N-(4-chlorobenzyl)-2-(((2-(4-(dimethylamino)phenyl)-2-oxoethyl)(methyl)amino)methyl)-7-methyl-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamide (672326-32-8) → C28H31ClN4O3S

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; chloroform; for 1h;

upstream raw materials:

N-(4-chlorobenzyl)-7-methyl-2-((methylamino)methyl)-4-oxo-4,7-dihydrothieno[2,3-b]-pyridine-5-carboxamide

2-bromo-1-(4-(dimethylamino)phenyl)ethanone

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