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Carmicheline

Base Information
  • Chemical Name:Carmicheline
  • CAS No.:39089-30-0
  • Molecular Formula:C22H35NO4
  • Molecular Weight:377.524
  • Hs Code.:
  • DSSTox Substance ID:DTXSID20959905
  • Wikidata:Q27107081
  • Metabolomics Workbench ID:53240
  • Mol file:39089-30-0.mol
Carmicheline

Synonyms:Karakoline;Carmicheline;Karacoline;Carmichaeline;39089-30-0;Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1-alpha,14-alpha,16-beta)-;20-ethyl-16beta-methoxy-4-methylaconitane-1alpha,8,14alpha-triol;CHEBI:6113;DTXSID20959905;C08693;Q27107081;(1S,2R,3R,4S,5S,6S,8S,9S,13R,16S,17R)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8,16-triol

Suppliers and Price of Carmicheline
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Karacoline
  • 1mg
  • $ 140.00
  • TRC
  • Karacoline
  • 10mg
  • $ 580.00
  • ChemScene
  • Karacoline
  • 10mg
  • $ 743.00
  • ChemScene
  • Karacoline
  • 5mg
  • $ 457.00
  • AvaChem
  • Karacoline
  • 5mg
  • $ 219.00
  • AvaChem
  • Karacoline
  • 20mg
  • $ 449.00
  • Arctom
  • Karacoline
  • 10mg
  • $ 288.00
  • ApexBio Technology
  • Karacoline
  • 20mg
  • $ 600.00
  • American Custom Chemicals Corporation
  • KARAKOLINE 95.00%
  • 5MG
  • $ 500.60
Total 25 raw suppliers
Chemical Property of Carmicheline
Chemical Property:
  • Vapor Pressure:6.38E-14mmHg at 25°C 
  • Melting Point:185-186℃ (acetone ) 
  • Boiling Point:540.2°Cat760mmHg 
  • PKA:13.80±0.70(Predicted) 
  • Flash Point:280.5°C 
  • PSA:73.16000 
  • Density:1.3g/cm3 
  • LogP:1.18850 
  • Storage Temp.:2-8°C 
  • XLogP3:1.1
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:2
  • Exact Mass:377.25660860
  • Heavy Atom Count:27
  • Complexity:673
Purity/Quality:

99%, *data from raw suppliers

Karacoline *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)O)C
  • Isomeric SMILES:CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2C[C@@H](C31)[C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@H]5[C@H]6O)OC)O)O)C
  • Description A second atisine base found in the tubers of Aconitum karacolicum, the structure has been elucidated from chemical and spectroscopic data. Oxidation with KMn04 gives anhydroepoxykaracoline. The alkaloid furnishes a triacetyl deriva_x0002_tive which, after pyrolysis and hydrolysis, yields acetyldemethylisopyrokaracoline.
  • Uses Karacoline is an Aconitane (A189875) derivative, which is a neurotoxin which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.
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