6,7-Dichloro-1,4-benzodioxan-2-methanol

Base Information

Chemical Name:6,7-Dichloro-1,4-benzodioxan-2-methanol
CAS No.:2164-37-6
Molecular Formula:C9H8Cl2O3
Molecular Weight:235.064
Hs Code.:
NSC Number:663622
DSSTox Substance ID:DTXSID60944234
Nikkaji Number:J71.431C
ChEMBL ID:CHEMBL1999269

Synonyms:2164-37-6;6,7-Dichloro-1,4-benzodioxan-2-methanol;NSC663622;BRN 1244761;1,4-BENZODIOXAN-2-METHANOL, 6,7-DICHLORO-;(6,7-Dichloro-2,3-dihydro-1,4-benzodioxin-2-yl)methanol;(6,7-dichloro-2,3-dihydro-1,4-benzodioxin-3-yl)methanol;SCHEMBL8131205;CHEMBL1999269;DTXSID60944234;NSC-663622;LS-34411;NCI60_021841;6,7-Dichloro-1,4-benzodioxane-2-methanol;(6,7-Dichloro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol

Suppliers and Price of 6,7-Dichloro-1,4-benzodioxan-2-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 6,7-Dichloro-1,4-benzodioxan-2-methanol

Chemical Property:

Vapor Pressure:1.07E-05mmHg at 25°C
Boiling Point:356.4°Cat760mmHg
Flash Point:169.4°C
Density:1.461g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:233.9850495
Heavy Atom Count:14
Complexity:203

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC2=CC(=C(C=C2O1)Cl)Cl)CO

Technology Process of 6,7-Dichloro-1,4-benzodioxan-2-methanol

There total 6 articles about 6,7-Dichloro-1,4-benzodioxan-2-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.4%

: C₁₁H₁₀Cl₂O₄

: 2164-37-6
6,7-dichloro-2-hydroxymethyl-1,4-benzodioxane

Guidance literature:: With sodium hydroxide; In methanol; water; at 20 ℃; for 3h;
DOI:10.1016/j.ejmech.2016.03.068

Reference yield:

: C₁₁H₁₀Cl₂O₃

: 2164-37-6
6,7-dichloro-2-hydroxymethyl-1,4-benzodioxane

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 18 h / 20 °C / Reflux

2: sodium hydroxide / methanol; water / 3 h / 20 °C

With 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; In methanol; dichloromethane; water; 1: |Baeyer-Villiger Ketone Oxidation;
DOI:10.1016/j.ejmech.2016.03.068

Reference yield:

: 22526-30-3
1-(4,5-dichloro-2-hydroxyphenyl)ethanone

: 2164-37-6
6,7-dichloro-2-hydroxymethyl-1,4-benzodioxane

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 18 h / 40 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 18 h / 20 °C / Reflux

3.1: sodium hydroxide / methanol; water / 3 h / 20 °C

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; 2.1: |Baeyer-Villiger Ketone Oxidation;
DOI:10.1016/j.ejmech.2016.03.068