2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Base Information

Chemical Name:2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
CAS No.:131063-65-5
Molecular Formula:C13H25 N O9
Molecular Weight:339.34
Hs Code.:
DSSTox Substance ID:DTXSID30927059
Mol file:131063-65-5.mol

Synonyms:(2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl)glucopyranoside;2-ADHMCG;2-amino-2,5,6-trideoxy-1-O-alpha-D-glucopyranosyl-5-(hydroxymethyl)-D-chiro-inositol;alpha-D-glucopyranosyl L-chiro-inositol isomer of (2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl)glucopyranoside;beta-D-glucopyranosyl D-chiro-inositol isomer of (2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl)glucopyranoside;beta-D-glucopyranosyl L-chiro-inositol isomer of (2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl)glucopyranoside

Suppliers and Price of 2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Chemical Property:

Vapor Pressure:5.4E-18mmHg at 25°C
Boiling Point:620.5°Cat760mmHg
Flash Point:329.1°C
PSA：186.09000
Density:1.61g/cm³
LogP:-4.06690
XLogP3:-3.8
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:4
Exact Mass:339.15293138
Heavy Atom Count:23
Complexity:387

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(C(C1OC2C(C(C(C(O2)CO)O)O)O)N)O)O)CO

Technology Process of 2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

There total 9 articles about 2-[2-Amino-3,4-dihydroxy-5-(hydroxymethyl)cyclohexyl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 101924-32-7,101978-70-5,116183-94-9,116183-95-0,131063-66-6,131063-76-8
<(1S)-(1,2,4/3,5)-2-Acetamido-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl> α-D-glucopyranoside heptaacetate

: 131063-65-5
<(1S)-(1,2,4/3,5)-2-Amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl> α-D-glucopyranoside

Guidance literature:: With hydrazine hydrate; at 70 ℃; for 1.5h;
DOI:10.1016/0008-6215(90)80074-D

Reference yield: 58.0%

: 116163-49-6
<(1S)-(1,2,4/3,5)-2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl> α-D-mannopyranoside

: 116163-49-6,116258-18-5,131063-65-5,131063-67-7,131063-72-4,131063-75-7
<(1R)-(1,2,4/3,5)-2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl> α-D-mannopyranoside

Guidance literature:: With hydrazine hydrate; In water; at 70 ℃; for 0.5h;
DOI:10.1016/0008-6215(87)85010-3

Reference yield:

: 14218-11-2,14218-30-5,61198-88-7,108438-33-1,108836-02-8,114682-36-9,127305-34-4,151377-77-4
2,3,4,6-Tetra-O-benzoyl-α-D-mannopyranosyl bromide

: 116163-49-6,116258-18-5,131063-65-5,131063-67-7,131063-72-4,131063-75-7
<(1R)-(1,2,4/3,5)-2-amino-3,4-dihydroxy-5-hydroxymethyl-1-cyclohexyl> α-D-mannopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: 84 percent / mercury(II) cyanide, Drierite / benzene / 64 h / Heating

2: 64 percent / sodium acetate / dimethylformamide / 15 h / 80 °C

3: 1.) sodium methoxide, 2.) pyridine / 1.) methanol, room temp., 2 h; 2.) room temp.

4: pyridine

5: 58 percent / hydrazine hydrate / H₂O / 0.5 h / 70 °C

6: 58 percent / hydrazine hydrate / H₂O / 0.5 h / 70 °C

With pyridine; calcium sulfate; sodium methylate; sodium acetate; mercury(II) cyanide; hydrazine hydrate; In water; N,N-dimethyl-formamide; benzene;
DOI:10.1016/0008-6215(87)85010-3