Pyoluteorin

Base Information

Chemical Name:Pyoluteorin
CAS No.:25683-07-2
Molecular Formula:C11H7Cl2NO3
Molecular Weight:272.087
Hs Code.:2933990090
NSC Number:143092
UNII:3YM4R964TU
DSSTox Substance ID:DTXSID30180384
Nikkaji Number:J20.016F
Wikipedia:Pyoluteorin
Wikidata:Q55086394
Metabolomics Workbench ID:117068
ChEMBL ID:CHEMBL2286204
Mol file:25683-07-2.mol

Synonyms:pyoluteorin

Suppliers and Price of Pyoluteorin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Pyoluteorin
25mg
$ 1455.00

Medical Isotopes, Inc.
Pyoluteorin
100 mg
$ 2200.00

Cayman Chemical
Pyoluteorin ≥98%
5mg
$ 975.00

Cayman Chemical
Pyoluteorin ≥98%
1mg
$ 249.00

ApexBio Technology
Pyoluteorin
5mg
$ 1351.00

ApexBio Technology
Pyoluteorin
1mg
$ 345.00

American Custom Chemicals Corporation
PYOLUTEORIN 95.00%
5MG
$ 502.59

AK Scientific
Pyoluteorin
5mg
$ 1416.00

AK Scientific
Pyoluteorin
1mg
$ 436.00

Total 17 raw suppliers

Chemical Property of Pyoluteorin

Chemical Property:

Vapor Pressure:3.06E-08mmHg at 25°C
Melting Point:174-175 °C (decomp)
Refractive Index:1.694
Boiling Point:436.9 °C at 760 mmHg
PKA:6.97±0.35(Predicted)
Flash Point:218 °C
PSA：73.32000
Density:1.632 g/cm³
LogP:2.96370
Solubility.:Soluble in DMSO
XLogP3:3.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:270.9802985
Heavy Atom Count:17
Complexity:292

Purity/Quality:

99% ^*data from raw suppliers

Pyoluteorin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)O)C(=O)C2=CC(=C(N2)Cl)Cl)O
Uses Pyoluteorin is a small chlorinated pyrrol produced by several species of Pseudomonas, first reported in 1958. Pyoluteorin exhibits a broad bioprofile, demonstrating antibiotic, antifungal and herbicidal activity. More recently, pyoluteorin has been investigated as bio-pesticide and has been shown to modulate the levels of metabolites in Pseudomonas.

Technology Process of Pyoluteorin

There total 7 articles about Pyoluteorin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 27667-11-4
pyoluteorin O,O-diacetate

: 25683-07-2
pyoluteorin

Guidance literature:: With hydrogenchloride; In methanol; for 2h; Heating;
DOI:10.1002/jhet.5570180136

Reference yield:

: 78225-54-4
2-<2',6'-dihydroxybenzoyl>pyrrole

: 25683-07-2
pyoluteorin

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / triethylamine / ethyl acetate / 2 h / 25 °C

2: 74 percent / N-chlorosuccinimide / CHCl₃ / 3 h / Heating

3: 95 percent / aq. conc. HCl / methanol / 2 h / Heating

With hydrogenchloride; N-chloro-succinimide; triethylamine; In methanol; chloroform; ethyl acetate;
DOI:10.1002/jhet.5570180136

Reference yield:

: 27667-09-0
2-<2',6'-dimethoxybenzoyl>pyrrole

: 25683-07-2
pyoluteorin

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / benzene, aluminium bromide / benzene / 5 h / Ambient temperature

2: 86 percent / triethylamine / ethyl acetate / 2 h / 25 °C

3: 74 percent / N-chlorosuccinimide / CHCl₃ / 3 h / Heating

4: 95 percent / aq. conc. HCl / methanol / 2 h / Heating

With hydrogenchloride; N-chloro-succinimide; aluminum tri-bromide; triethylamine; benzene; In methanol; chloroform; ethyl acetate; benzene;
DOI:10.1002/jhet.5570180136