(2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate

Base Information

Chemical Name:(2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate
CAS No.:3916-18-5
Molecular Formula:C₉H₁₁NO₅
Molecular Weight:213.19
Hs Code.:
Pharos Ligand ID:R9GN68J12MVK
Metabolomics Workbench ID:149711
Mol file:3916-18-5.mol

Synonyms:

Suppliers and Price of (2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
DL-threo-Droxidopa
25mg
$ 175.00

Sigma-Aldrich
DL-3,4-Dihydroxyphenylserine ≥98% (HPLC), powder
1 g
$ 1470.00

American Custom Chemicals Corporation
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE 95.00%
250MG
$ 1871.10

American Custom Chemicals Corporation
BETA-D,L-(3,4-DIHYDROXYPHENYL)-SERINE 95.00%
25MG
$ 739.20

Total 12 raw suppliers

Chemical Property of (2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate

Chemical Property:

Vapor Pressure:6.39E-13mmHg at 25°C
Melting Point:>200oC
Refractive Index:1.692
Boiling Point:549.8 °C at 760 mmHg
PKA:2.09±0.24(Predicted)
Flash Point:286.3 °C
PSA：124.01000
Density:1.608 g/cm³
LogP:0.24340
Storage Temp.:-15°C
Solubility.:ethanol: 50 mg/mL Solutions should be freshly prepared.
XLogP3:-3.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:213.06372245
Heavy Atom Count:15
Complexity:229

Purity/Quality:

99% ^*data from raw suppliers

DL-threo-Droxidopa ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(C(C(=O)[O-])[NH3+])O)O)O
Isomeric SMILES:C1=CC(=C(C=C1[C@H]([C@@H](C(=O)[O-])[NH3+])O)O)O
Uses A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian.

Technology Process of (2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate

There total 6 articles about (2S,3R)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5447-02-9
3,4-dibenzyloxybenzaldehyde

: 492-46-6,3916-18-5,6204-89-3,13147-26-7,16322-99-9,23651-95-8,34047-62-6,34124-73-7,50731-20-9,51829-98-2,51829-99-3,89886-54-4
(+/-)-threo-DOPS

Guidance literature:: Multi-step reaction with 2 steps

1: aq.-ethanolic NaOH / anschliessendes Erwaermen mit wss. HCl

2: palladium; aqueous methanol / Hydrogenation

With methanol; sodium hydroxide; palladium;