Technology Process of 2-Pyrrolidinone, 5-(aminomethyl)-1-methyl-, (R)-
There total 6 articles about 2-Pyrrolidinone, 5-(aminomethyl)-1-methyl-, (R)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
palladium 10% on activated carbon;
In
methanol;
at 20 ℃;
for 14h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium azide / water; tetrahydrofuran / 16 h / 80 °C
2: palladium 10% on activated carbon / methanol / 14 h / 20 °C
With
sodium azide;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; water;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: thionyl chloride / 17 h / 0 - 20 °C
2: potassium carbonate / acetonitrile / 72 h / 80 °C
3: sodium tetrahydroborate; methanol / 4 h / 0 - 20 °C
4: triethylamine; methanesulfonyl chloride / dichloromethane / 3.5 h / 0 - 20 °C
5: sodium azide / water; tetrahydrofuran / 16 h / 80 °C
6: palladium 10% on activated carbon / methanol / 14 h / 20 °C
With
methanol; sodium tetrahydroborate; thionyl chloride; sodium azide; potassium carbonate; methanesulfonyl chloride; triethylamine;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;