1-(Ethoxyethynyl)-4-methylbenzene

Base Information

Chemical Name:1-(Ethoxyethynyl)-4-methylbenzene
CAS No.:67500-32-7
Molecular Formula:C11H12O
Molecular Weight:160.216
Hs Code.:
DSSTox Substance ID:DTXSID00496762
Nikkaji Number:J470.752D
Wikidata:Q82345853

Synonyms:67500-32-7;1-(Ethoxyethynyl)-4-methylbenzene;DTXSID00496762

Suppliers and Price of 1-(Ethoxyethynyl)-4-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(Ethoxyethynyl)-4-methylbenzene

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:160.088815002
Heavy Atom Count:12
Complexity:176

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC#CC1=CC=C(C=C1)C

Technology Process of 1-(Ethoxyethynyl)-4-methylbenzene

There total 5 articles about 1-(Ethoxyethynyl)-4-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 624-31-7
4-tolyl iodide

: 23268-50-0
Ethyl(trimethylstannylethinyl)ether

: 67500-32-7
1-(ethoxyethynyl)-4-methylbenzene

Guidance literature:: With PdCl₂(PPh)3; tetraethylammonium chloride; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1248/cpb.42.2032

Reference yield: 45.0%

: 624-31-7
4-tolyl iodide

: 137344-20-8
ethoxy(tributylstannyl)acetylene

: 67500-32-7
1-(ethoxyethynyl)-4-methylbenzene

Guidance literature:: With PdCl₂(PPh)3; tetraethylammonium chloride; In N,N-dimethyl-formamide; for 15h; Ambient temperature;
DOI:10.1248/cpb.42.2032

Reference yield:

: 42345-82-4
(E)-1,2-dichloro-1-ethoxy-ethene

: 624-31-7
4-tolyl iodide

: 67500-32-7
1-(ethoxyethynyl)-4-methylbenzene

Guidance literature:: With n-butyllithium; triphenylphosphine; zinc(II) chloride; bis-triphenylphosphine-palladium(II) chloride; Yield given. Multistep reaction; 1) a) THF, hexane, -70 deg C, 15 min, b) 0 deg C, 5 min, 2) room temperature, 4 h;