norbenzphetamine

Base Information

• Chemical Name: norbenzphetamine
• CAS No.: 1085-42-3
• Molecular Formula: C16H19 N
• Molecular Weight: 225.334
• European Community (EC) Number: 855-508-2
• UNII: 1OV1CK7BED
• DSSTox Substance ID: DTXSID40910755
• Nikkaji Number: J13.147D
• Wikidata: Q27895620
• Mol file: 1085-42-3.mol

Synonyms:Phenethylamine,N-benzyl-a-methyl- (7CI,8CI);1-Phenyl-2-(benzylamino)propane; 1-Phenyl-2-(phenylmethylamino)propane;Benzylamphetamine; N-Benzyl-a-methylphenethylamine; N-Benzylamphetamine; Norbenzphetamine

Chemical Property of norbenzphetamine

Chemical Property:

• Vapor Pressure: 9.49E-05mmHg at 25°C
• Boiling Point: 339°Cat760mmHg
• Flash Point: 157.4°C
• PSA: 12.03000
• Density: 1g/cm³
• LogP: 3.79830
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 225.151749610
• Heavy Atom Count: 17
• Complexity: 190

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Benzyl-1-phenylpropan-2-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)NCC2=CC=CC=C2

Technology Process of norbenzphetamine

There total 18 articles about norbenzphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

benzylamine (100-46-9) + 1-phenyl-acetone (103-79-7,136675-26-8) → 1-phenyl-2-benzylaminopropane (1085-42-3)

Guidance literature:

With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jm070030d

Reference yield: 91.0%

→ 1-phenyl-2-benzylaminopropane (1085-42-3)

Guidance literature:

Reference yield: 88.0%

(2-azido-2-methylpropane-1,3-diyl)dibenzene → 1-phenyl-2-benzylaminopropane (1085-42-3)

Guidance literature:

(2-azido-2-methylpropane-1,3-diyl)dibenzene; With trifluoromethylsulfonic anhydride; In dimethyl sulfoxide; at 50 ℃; for 4h;

With sodium tetrahydroborate; acetic acid; In dimethyl sulfoxide; at 0 ℃; for 2h;

DOI:10.1039/d1cc02770k

upstream raw materials:

benzaldehyde

2-amino-1-phenylpropane

benzylamine

1-phenyl-acetone

Downstream raw materials:

4-{2-[Benzyl-(1-methyl-2-phenyl-ethyl)-amino]-1-hydroxy-ethyl}-2-(2-hydroxy-ethoxy)-phenol

2-(2-Hydroxy-ethoxy)-4-[1-hydroxy-2-(1-methyl-2-phenyl-ethylamino)-ethyl]-phenol

C₃₈H₃₉NO₃

C₃₈H₃₉NO₃