Cyclopropane, 1,1-(3-methylene-1-propyne-1,3-diyl)bis- (9CI)

Base Information

• Chemical Name: Cyclopropane, 1,1-(3-methylene-1-propyne-1,3-diyl)bis- (9CI)
• CAS No.: 67539-02-0
• Molecular Formula: C10H12
• Molecular Weight: 132.205
• Mol file: 67539-02-0.mol

Synonyms:2,4-dicyclopropyl-1-buten-3-yne;2,4-Dicyclopropyl-1-buten-3-in;

Chemical Property of Cyclopropane, 1,1-(3-methylene-1-propyne-1,3-diyl)bis- (9CI)

Chemical Property:

• Boiling Point: 98 °C (10 mmHg)
• PSA: 0.00000
• LogP: 2.36600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropane, 1,1-(3-methylene-1-propyne-1,3-diyl)bis- (9CI)

There total 5 articles about Cyclopropane, 1,1-(3-methylene-1-propyne-1,3-diyl)bis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cyclopropylacetylene (6746-94-7) → (gem)-1,3-dicyclopropylbut-1-yn-3-ene (67539-02-0)

Guidance literature:

palladium diacetate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 12h; Product distribution; other catalysts, other temperatures, other solvents;

DOI:10.1007/BF00962138

Reference yield:

Cyclopropylacetylene (6746-94-7) → (gem)-1,3-dicyclopropylbut-1-yn-3-ene (67539-02-0) + C10H12

Guidance literature:

With C₄₃H₅₈N₃ORh; In benzene-d6; at 25 ℃; for 2h; Schlenk technique;

DOI:10.1002/chem.202001584

Reference yield:

Cyclopropyl methyl ketone (765-43-5) → (gem)-1,3-dicyclopropylbut-1-yn-3-ene (67539-02-0)

Guidance literature:

Multi-step reaction with 2 steps

1: nBuLi / tetrahydrofuran; hexane

2: HMPA

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1007/BF00923368

upstream raw materials:

2,4-Dicyclopropyl-3-butyn-2-ol

Cyclopropylacetylene

Cyclopropyl methyl ketone

2-vinylpyrazine