Amphenone B

Base Information

• Chemical Name: Amphenone B
• CAS No.: 2686-47-7
• Molecular Formula: C₁₆H₁₈N₂O
• Molecular Weight: 254.332
• Hs Code.: 2922399090
• UNII: Y2YUN941SL
• DSSTox Substance ID: DTXSID70181370
• Nikkaji Number: J354.054E
• Wikipedia: Amphenone_B
• Wikidata: Q27105763
• Metabolomics Workbench ID: 67664
• Mol file: 2686-47-7.mol

Synonyms:amphenone;amphenone B

Chemical Property of Amphenone B

Chemical Property:

• Vapor Pressure: 4.16E-08mmHg at 25°C
• Melting Point: 137.5-138°
• Boiling Point: 444.8°Cat760mmHg
• Flash Point: 222.8°C
• PSA: 69.11000
• Density: 1.151g/cm³
• LogP: 3.90840
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 254.141913202
• Heavy Atom Count: 19
• Complexity: 291

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C(C)(C1=CC=C(C=C1)N)C2=CC=C(C=C2)N

Technology Process of Amphenone B

There total 4 articles about Amphenone B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-bis-(4-amino-phenyl)-butane-2,3-diol; dihydrochloride (109563-47-5) → amphenone (2686-47-7)

Guidance literature:

With water;

DOI:10.1021/ja01157a033

Reference yield:

3,3-bis(4-nitrophenyl)-2-butanone (93014-47-2) → amphenone (2686-47-7)

Guidance literature:

With 1,4-dioxane; palladium on activated charcoal; Hydrogenation;

DOI:10.1021/jo01359a002

Reference yield:

3,3-diphenylbutan-2-one (2575-20-4) → amphenone (2686-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; HNO₃

2: palladium/charcoal; dioxane / Hydrogenation

With 1,4-dioxane; palladium on activated charcoal; sulfuric acid; nitric acid;

DOI:10.1021/jo01359a002

upstream raw materials:

3,3-bis(4-nitrophenyl)-2-butanone

2,3-bis-(4-amino-phenyl)-butane-2,3-diol; dihydrochloride

water

3,3-diphenylbutan-2-one