IPROVALICARB

Base Information

• Chemical Name: IPROVALICARB
• CAS No.: 140923-25-7
• Molecular Formula: C₁₈H₂₈N₂O₃
• Molecular Weight: 320.432
• Mol file: 140923-25-7.mol

Synonyms:Carbamicacid, [2-methyl-1-[[[1-(4-methylphenyl)ethyl]amino]carbonyl]propyl]-,1-methylethyl ester, [S-(R*,S*)]-

Chemical Property of IPROVALICARB

Chemical Property:

• Vapor Pressure: 4.8E-10mmHg at 25°C
• Boiling Point: 497.8°Cat760mmHg
• PKA: 11.41±0.46(Predicted)
• Flash Point: 254.8°C
• PSA: 74.41000
• Density: 1.043g/cm³
• LogP: 4.37610

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of IPROVALICARB

There total 3 articles about IPROVALICARB which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → iprovalicarb (140923-17-7,140923-25-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / tetrahydrofuran; water / 20 °C

2: isopropyl chloroformate / tetrahydrofuran

With isopropyl chloroformate; potassium hydroxide; In tetrahydrofuran; water;

DOI:10.1016/j.bmcl.2015.10.089

Reference yield:

1-(p-tolyl)ethylamine (42070-98-4) + N-isopropoxycarbonyl-S-valine (140923-27-9) → iprovalicarb (140923-17-7,140923-25-7)

Guidance literature:

N-isopropoxycarbonyl-S-valine; With isopropyl chloroformate; In tetrahydrofuran;

1-(p-tolyl)ethylamine; With triethylamine; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2015.10.089

Reference yield:

→ isopropyl 2-methyl-1-[(1-p-tolylethyl)carbamoyl]-(s)-propylcarbamate (140923-25-7)

Guidance literature:

upstream raw materials:

1-(p-tolyl)ethylamine

N-isopropoxycarbonyl-S-valine

L-valine

Refernces

• 1、 -. "Synergistic Combinations Of Active Ingredients". . . Retrieved 2012/02/15.