dihydro-

Base Information

• Chemical Name: dihydro-
• CAS No.: 63335-66-0
• Molecular Formula: C₁₃H₂₂O
• Molecular Weight: 194.317
• Mol file: 63335-66-0.mol

Synonyms:

Chemical Property of dihydro-

Chemical Property:

• PSA: 9.23000
• LogP: 3.54630

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dihydro-

There total 11 articles about dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

dihydro-α-ionol (13720-37-1) → 2,6,10,10-tetramethyl-1-oxaspiro[4.5]dec-6-ene (36431-72-8,59872-09-2,79516-57-7,169102-88-9,43126-21-2,43126-22-3,66537-39-1,66537-40-4) + dl-dihydroedulan (41678-32-4,63335-66-0,72746-44-2,74006-61-4,74006-62-5,122797-82-4)

Guidance literature:

With bis(p-chlorophenyl) diselenide; tetraethylammonium perchlorate; In water; acetonitrile; at 65 - 70 ℃; electrochemical oxidation;

DOI:10.1016/S0040-4039(00)98772-0

Reference yield: 20.0%

3',4'-dehydro-2'-hydroxy-2',3',3,4-tetrahydro-α-ionol → dl-dihydroedulan (41678-32-4,63335-66-0,72746-44-2,74006-61-4,74006-62-5,122797-82-4) + (+/-)-dihydroedulan II

Guidance literature:

With acetic acid; for 16h;

Reference yield:

(1S,6S)-6-(4-Chloro-phenylselanyl)-2-(3-hydroxy-butyl)-1,3,3-trimethyl-cyclohexanol → dl-dihydroedulan (41678-32-4,63335-66-0,72746-44-2,74006-61-4,74006-62-5,122797-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: formic acid / boron trifluoride

2: 18 percent / bis(p-chlorophenyl)diselenide / Et₄NClO₄ / CH₂Cl₂ / electrochemical oxidation

With formic acid; bis(p-chlorophenyl) diselenide; boron trifluoride; tetraethylammonium perchlorate; In dichloromethane;

DOI:10.1016/S0040-4039(00)98772-0

upstream raw materials:

dihydro-α-ionol

(2R,4aR,8R,8aR)-8-(4-Chloro-phenylselanyl)-2,5,5,8a-tetramethyl-octahydro-chromene

9-hydroxymegastigma-4,7-dien-3-one

Refernces

• 1、 Etoh, Hideo,Ina, Kazuo,Iguchi, Masanobu. "New Syntheses of Edulans and Theaspiranes from α-Inone". . p. 2871 - 2876. Retrieved 2007/10/02.