5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)-

Base Information

• Chemical Name: 5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)-
• CAS No.: 675868-68-5
• Molecular Formula: C₁₁H₂₂O₂
• Molecular Weight: 186.294

Synonyms:

Chemical Property of 5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)-

Chemical Property:

• Boiling Point: 258.6±33.0 °C(Predicted)
• PSA: 29.46000
• Density: 0.895±0.06 g/cm3(Predicted)
• LogP: 2.37620

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)-

There total 1 articles about 5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Butyric acid (E)-7-methoxy-3,7-dimethyl-oct-5-enyl ester → trans-2,6-dimethyl-2-methoxy-3-octen-8-ol (675868-68-5) + Butyric acid (E)-(S)-7-methoxy-3,7-dimethyl-oct-5-enyl ester

Guidance literature:

With pig liver acetone;

DOI:10.1080/00397910500186425

Reference yield:

trans-2,6-dimethyl-2-methoxy-3-octen-8-ol (675868-68-5) → (2R,3S,4E,6R,8R,10R,12Z)-2-((R,1E,5E)-8-(2-bromo-3-hydroxyphenyl)-8-hydroxy-7,7-dimethylocta-1,5-dien-3-yn-1-yl)-3,6,10-trimethyl-14-oxooxacyclotetradeca-4,12-dien-8-yl carbamate

Guidance literature:

Multi-step reaction with 17 steps

1.1: C₄₉H₃₇Cl₂IrN₂O₆P₂; potassium phosphate / tetrahydrofuran / 144 h / 55 °C / Sealed tube; Inert atmosphere

2.1: diethyl ether / 1 h / -78 - -20 °C / Inert atmosphere

3.1: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 50 °C / Inert atmosphere

4.1: Wilkinson's catalyst; hydrogen / dichloromethane / 3 h / 20 °C / 15001.5 Torr

5.1: ozone / dichloromethane / -78 °C

5.2: 20 °C / Inert atmosphere

5.3: 0 - 20 °C / Inert atmosphere

6.1: pyridinium p-toluenesulfonate; dihydrogen peroxide / acetonitrile; water / 1 h / 20 °C / Inert atmosphere

7.1: methanol / 20 °C / Inert atmosphere

7.2: 20 °C / Inert atmosphere

8.1: potassium carbonate / methanol / 20 h / 20 °C / Inert atmosphere

9.1: palladium diacetate; copper dichloride / 1,2-dichloro-ethane / 0.25 h / 20 °C / Molecular sieve; Inert atmosphere

9.2: 24 h / 20 - 40 °C / Inert atmosphere

10.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere

11.1: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

11.2: 20 °C / Inert atmosphere

12.1: pyridine hydrofluoride / 2 h / 0 - 20 °C / Inert atmosphere

13.1: acetone / 0.33 h / 20 °C / UV-irradiation; Inert atmosphere

14.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

14.2: 0.33 h / -78 - 20 °C / Inert atmosphere

15.1: tetrahydrofuran; toluene / -78 - 20 °C / Inert atmosphere

16.1: acetic acid; tetrabutyl ammonium fluoride / tetrahydrofuran; toluene / 1 h / 20 °C / Inert atmosphere

17.1: pyrrolidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 4 h / 20 °C / Inert atmosphere

With pyrrolidine; potassium phosphate; copper(l) iodide; Wilkinson's catalyst; tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxalyl dichloride; pyridine hydrofluoride; C₄₉H₃₇Cl₂IrN₂O₆P₂; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; palladium diacetate; pyridinium p-toluenesulfonate; potassium carbonate; ozone; acetic acid; dimethyl sulfoxide; copper dichloride; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; 1,2-dichloro-ethane; acetone; toluene; acetonitrile; 14.1: |Swern Oxidation / 14.2: |Swern Oxidation / 17.1: |Sonogashira Cross-Coupling;

DOI:10.1021/jacs.7b13591

Reference yield:

trans-2,6-dimethyl-2-methoxy-3-octen-8-ol (675868-68-5) → (2R,3S,4E,6R,8R,10R,12E)-2-((R,1E,5E)-8-(2-bromo-3-hydroxyphenyl)-8-hydroxy-7,7-dimethylocta-1,5-dien-3-yn-1-yl)-3,6,10-trimethyl-14-oxooxacyclotetradeca-4,12-dien-8-yl carbamate

Guidance literature:

Multi-step reaction with 16 steps

1.1: C₄₉H₃₇Cl₂IrN₂O₆P₂; potassium phosphate / tetrahydrofuran / 144 h / 55 °C / Sealed tube; Inert atmosphere

2.1: diethyl ether / 1 h / -78 - -20 °C / Inert atmosphere

3.1: pyridinium p-toluenesulfonate / tetrahydrofuran / 2.5 h / 50 °C / Inert atmosphere

4.1: Wilkinson's catalyst; hydrogen / dichloromethane / 3 h / 20 °C / 15001.5 Torr

5.1: ozone / dichloromethane / -78 °C

5.2: 20 °C / Inert atmosphere

5.3: 0 - 20 °C / Inert atmosphere

6.1: pyridinium p-toluenesulfonate; dihydrogen peroxide / acetonitrile; water / 1 h / 20 °C / Inert atmosphere

7.1: methanol / 20 °C / Inert atmosphere

7.2: 20 °C / Inert atmosphere

8.1: potassium carbonate / methanol / 20 h / 20 °C / Inert atmosphere

9.1: palladium diacetate; copper dichloride / 1,2-dichloro-ethane / 0.25 h / 20 °C / Molecular sieve; Inert atmosphere

9.2: 24 h / 20 - 40 °C / Inert atmosphere

10.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere

11.1: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

11.2: 20 °C / Inert atmosphere

12.1: pyridine hydrofluoride / 2 h / 0 - 20 °C / Inert atmosphere

13.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

13.2: 0.33 h / -78 - 20 °C / Inert atmosphere

14.1: tetrahydrofuran; toluene / -78 - 20 °C / Inert atmosphere

15.1: acetic acid; tetrabutyl ammonium fluoride / tetrahydrofuran; toluene / 1 h / 20 °C / Inert atmosphere

16.1: pyrrolidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 4 h / 20 °C / Inert atmosphere

With pyrrolidine; potassium phosphate; copper(l) iodide; Wilkinson's catalyst; tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxalyl dichloride; pyridine hydrofluoride; C₄₉H₃₇Cl₂IrN₂O₆P₂; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; palladium diacetate; pyridinium p-toluenesulfonate; potassium carbonate; ozone; acetic acid; dimethyl sulfoxide; copper dichloride; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; 1,2-dichloro-ethane; toluene; acetonitrile; 13.1: |Swern Oxidation / 13.2: |Swern Oxidation / 16.1: |Sonogashira Cross-Coupling;

DOI:10.1021/jacs.7b13591

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 675868-68-5 5-Octen-1-ol, 7-methoxy-3,7-dimethyl-, (3R,5E)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send