3-Biphenylacetic acid, 5-chloro-

Base Information

Chemical Name:3-Biphenylacetic acid, 5-chloro-
CAS No.:75852-51-6
Molecular Formula:C₁₄H₁₁ClO₂
Molecular Weight:246.693
Hs Code.:
DSSTox Substance ID:DTXSID70226755
Nikkaji Number:J78.972K
Wikidata:Q83106267
ChEMBL ID:CHEMBL141725
Mol file:75852-51-6.mol

Synonyms:3-BIPHENYLACETIC ACID, 5-CHLORO-;BRN 5005912;5-Chloro-3-biphenylacetic acid;75852-51-6;CHEMBL141725;DTXSID70226755;5-Chloro-1,1'-biphenyl-3-acetic acid;LS-44037

Suppliers and Price of 3-Biphenylacetic acid, 5-chloro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-CHLORO-3-BIPHENYLACETIC ACID 95.00%
5MG
$ 504.75

Total 3 raw suppliers

Chemical Property of 3-Biphenylacetic acid, 5-chloro-

Chemical Property:

Vapor Pressure:1.76E-07mmHg at 25°C
Boiling Point:410.7°C at 760 mmHg
Flash Point:202.2°C
PSA：37.30000
Density:1.27g/cm³
LogP:3.63410
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:246.0447573
Heavy Atom Count:17
Complexity:261

Purity/Quality:

99% ^*data from raw suppliers

5-CHLORO-3-BIPHENYLACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=CC(=C2)CC(=O)O)Cl

Technology Process of 3-Biphenylacetic acid, 5-chloro-

There total 4 articles about 3-Biphenylacetic acid, 5-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 75852-30-1
methyl 5-chloro-3-biphenylylacetate

: 75852-51-6
(5-Chloro-biphenyl-3-yl)-acetic acid

Guidance literature:: With sodium hydroxide; In methanol; for 1h; Heating;
DOI:10.1021/jm00133a010

Reference yield:

: 75852-22-1
methyl 5-acetamido-3-biphenylylacetate

: 75852-51-6
(5-Chloro-biphenyl-3-yl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: concd HCl / methanol / 4 h / Heating

2: HCl / 2 h / Heating

3: 1.) aq. NaNO₂, concd HCl, 2.) Cu₂Cl₂, aq. KCl / 1.) acetone, 0-5 deg C, 2.) acetone, a) 0-5 deg C, 2 h, b) 70-80 deg C, 0.5 h

With copper(I) chloride; hydrogenchloride; potassium chloride; sodium nitrite; In methanol;
DOI:10.1021/jm00133a010

Reference yield:

: 75852-25-4
methyl 5-amino-3-biphenylylacetate hydrochloride

: 75852-51-6
(5-Chloro-biphenyl-3-yl)-acetic acid

Guidance literature:: With copper(I) chloride; hydrogenchloride; potassium chloride; sodium nitrite; Yield given. Multistep reaction; 1.) acetone, 0-5 deg C, 2.) acetone, a) 0-5 deg C, 2 h, b) 70-80 deg C, 0.5 h;
DOI:10.1021/jm00133a010