Glycyphyllin

Base Information

Chemical Name:Glycyphyllin
CAS No.:19253-17-9
Molecular Formula:C21H24O9
Molecular Weight:420.4099
Hs Code.:
DSSTox Substance ID:DTXSID60331822
Nikkaji Number:J1.134.620K
Wikidata:Q27103108
Metabolomics Workbench ID:51302

Synonyms:Glycyphyllin;19253-17-9;Phloretin 2'-O-rhamnoside;1-[2,4-dihydroxy-6-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one;1-(2,4-dihydroxy-6-alpha-L-rhamnopyranosyloxyphenyl)-3-(4-hydroxyphenyl)propan-1-one;3,5-dihydroxy-2-[3-(4-methylphenyl)propanoyl]phenyl 6-deoxy-alpha-L-mannopyranoside;SCHEMBL108631;CHEBI:27400;DTXSID60331822;C09754;Q27103108

Suppliers and Price of Glycyphyllin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Glycyphyllin

Chemical Property:

Vapor Pressure:1.56E-21mmHg at 25°C
Boiling Point:716.3°Cat760mmHg
Flash Point:252.4°C
Density:1.491g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:420.14203234
Heavy Atom Count:30
Complexity:565

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(C(C(C(O1)OC2=CC(=CC(=C2C(=O)CCC3=CC=C(C=C3)O)O)O)O)O)O
Isomeric SMILES:C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC(=CC(=C2C(=O)CCC3=CC=C(C=C3)O)O)O)O)O)O

Technology Process of Glycyphyllin

There total 5 articles about Glycyphyllin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.6%

: 130471-80-6,138665-95-9,138665-96-0
2',4,4',6'-Tetrahydroxychalcone 2'-O-α-L-rhamnopyranoside

: 19253-17-9
phloretin 2'-O-(6-deoxy-α-L-mannopyranoside)

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 100h; under 760 Torr;

Reference yield:

: 130471-75-9
ο-Benzoyloxy-phloracetophenon

: 19253-17-9
phloretin 2'-O-(6-deoxy-α-L-mannopyranoside)

Guidance literature:: Multi-step reaction with 4 steps

1: 37.8 percent / mercuric cyanide, nitromethane / Heating

2: 0.1 N NaOMe / methanol / 2 h / Ambient temperature

3: 41.4 percent / KOH / ethanol / 96 h / Ambient temperature

4: 70.6 percent / H₂ / 10 percent Pd/C / methanol / 100 h / 760 Torr

With potassium hydroxide; nitromethane; hydrogen; sodium methylate; mercury(II) cyanide; palladium on activated charcoal; In methanol; ethanol;

Reference yield:

: 130471-77-1,130500-49-1
Benzoic acid 4-acetyl-3-hydroxy-5-((3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxy)-phenyl ester

: 19253-17-9
phloretin 2'-O-(6-deoxy-α-L-mannopyranoside)

Guidance literature:: Multi-step reaction with 3 steps

1: 0.1 N NaOMe / methanol / 2 h / Ambient temperature

2: 41.4 percent / KOH / ethanol / 96 h / Ambient temperature

3: 70.6 percent / H₂ / 10 percent Pd/C / methanol / 100 h / 760 Torr

With potassium hydroxide; hydrogen; sodium methylate; palladium on activated charcoal; In methanol; ethanol;