Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-

Base Information

Chemical Name:Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-
CAS No.:676446-95-0
Molecular Formula:C29H30N4O
Molecular Weight:450.583
Hs Code.:
DSSTox Substance ID:DTXSID10432095

Synonyms:676446-95-0;Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-;SCHEMBL6080077;DTXSID10432095;CRTFHNZNUSVPFV-UHFFFAOYSA-N;1-(2,2-Diphenyl-ethyl)-pyrrolidin-3-yl-3-(2-methyl-quinolin-4-yl)-urea

Suppliers and Price of Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:450.24196159
Heavy Atom Count:34
Complexity:626

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3CCN(C3)CC(C4=CC=CC=C4)C5=CC=CC=C5

Technology Process of Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)-

There total 4 articles about Urea, N-[1-(2,2-diphenylethyl)-3-pyrrolidinyl]-N'-(2-methyl-4-quinolinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(2-methyl-quinolin-4-yl)-3-pyrrolidin-3-yl-urea dihydrochloride

: 947-91-1
Diphenylacetaldehyde

: 676446-95-0
1-[1-(2,2-diphenyl-ethyl)-pyrrolidin-3-yl]-3-(2-methyl-quinolin-4-yl)-urea

Guidance literature:: With sodium tris(acetoxy)borohydride; triethylamine; In tetrahydrofuran; at 20 ℃; for 15h;

Reference yield:

: 1055727-00-8
3-[3-(2-methyl-quinolin-4-yl)-ureido]-pyrrolidine-1-carboxylic acid tert-butyl ester

: 676446-95-0
1-[1-(2,2-diphenyl-ethyl)-pyrrolidin-3-yl]-3-(2-methyl-quinolin-4-yl)-urea

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 3 h

2: sodium tris(acetoxy)borohydride; triethylamine / tetrahydrofuran / 15 h / 20 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; triethylamine; In tetrahydrofuran; 1,4-dioxane;

Reference yield:

: 6628-04-2
4-amino-2-methylquinoline

: 676446-95-0
1-[1-(2,2-diphenyl-ethyl)-pyrrolidin-3-yl]-3-(2-methyl-quinolin-4-yl)-urea

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran / 16.5 h / 20 °C / Heating / reflux

2: methanol / 15 h / Heating / reflux

3: hydrogenchloride / 1,4-dioxane / 3 h

4: sodium tris(acetoxy)borohydride; triethylamine / tetrahydrofuran / 15 h / 20 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol;