6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate

Base Information

Chemical Name:6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate
CAS No.:134749-18-1
Molecular Formula:C11H14ClN5O3
Molecular Weight:299.717
Hs Code.:
DSSTox Substance ID:DTXSID10158920

Synonyms:6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate;134749-18-1;Hydrazinecarboxamide, 2-(6,7-dimethoxy-4-quinazolinyl)-, monohydrochloride, dihydrate;2-(6,7-Dimethoxy-4-quinazolinyl)hydrazinecarboxamide monohydrochloride dihydrate;DTXSID10158920;C11H13N5O3.ClH.2H2O;LS-76597;C11-H13-N5-O3.Cl-H.2H2-O

Suppliers and Price of 6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:g/cm³
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:299.0785170
Heavy Atom Count:20
Complexity:317

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)C(=NC=N2)NNC(=O)N)OC.Cl

Technology Process of 6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate

There total 2 articles about 6,7-Dimethoxy-4-semicarbazidoquinazoline hydrochloride dihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.8%

: 134749-19-2
2-chloro-6,7-dimethoxy-4-semicarbazidoquinazoline

: 134749-18-1
6,7-dimethoxy-4-semicarbazidoquinazoline hydrochloride

Guidance literature:: With hydrogenchloride; hydrogen; palladium dichloride; In ethanol; water; for 1h; Ambient temperature;
DOI:10.1007/BF00766359

Reference yield:

: 27631-29-4
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one

: 134749-18-1
6,7-dimethoxy-4-semicarbazidoquinazoline hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / dimethylformamide / 24 h / Ambient temperature

2: 57.8 percent / HCl, H₂ / PdCl₂ / ethanol; H₂O / 1 h / Ambient temperature

With hydrogenchloride; hydrogen; palladium dichloride; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1007/BF00766359