Antibiotic MM-22380

Base Information

Chemical Name:Antibiotic MM-22380
CAS No.:63582-78-5
Molecular Formula:C13H18N2O5S
Molecular Weight:314.35742
Hs Code.:
Mol file:63582-78-5.mol

Synonyms:

Suppliers and Price of Antibiotic MM-22380

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Antibiotic MM-22380

Chemical Property:

PSA：132.24000
LogP:0.09220

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Antibiotic MM-22380

There total 9 articles about Antibiotic MM-22380 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 77359-12-7,84367-47-5
p-nitrobenzyl (+/-)-cis-3-(2-acetamidoethylthio)-6β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate

: 63582-78-5,63599-16-6,63701-32-6,74923-12-9,77448-04-5
(+/-)-epithienamycin A

Guidance literature:: With hydrogen; sodium hydrogencarbonate; platinum(IV) oxide; In tetrahydrofuran; for 1.5h; Pressure (range begins): 40 ; Ambient temperature;
DOI:10.1039/P19810002282

Reference yield:

: 76335-76-7,77448-00-1,79299-25-5,90581-13-8,150284-14-3
(+/-)-4β-carboxymethyl-3β-<(1S^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one

: 63582-78-5,63599-16-6,63701-32-6,74923-12-9,77448-04-5
(+/-)-epithienamycin A

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) N,N'-carbonyldiimidazole

2: p-toluenesulphonyl azide, triethylamine

3: rhodium diacetate

4: 4-dimethylaminopyridine, diisopropylethylamine / acetonitrile

5: diisopropylethylamine

6: NaHCO₃, H₂ / Adams catalyst / tetrahydrofuran; H₂O / 2068.6 Torr

With rhodium(II) acetate; dmap; 4-toluenesulfonyl azide; hydrogen; sodium hydrogencarbonate; triethylamine; N-ethyl-N,N-diisopropylamine; 1,1'-carbonyldiimidazole; platinum(IV) oxide; In tetrahydrofuran; water; acetonitrile;

Reference yield:

: 78072-36-3,96093-91-3,96093-95-7
(5R,6R)-3-(Diphenoxy-phosphoryloxy)-6-[(S)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

: 63582-78-5,63599-16-6,63701-32-6,74923-12-9,77448-04-5
(+/-)-epithienamycin A

Guidance literature:: Multi-step reaction with 2 steps

1: diisopropylethylamine

2: NaHCO₃, H₂ / Adams catalyst / tetrahydrofuran; H₂O / 2068.6 Torr

With hydrogen; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; platinum(IV) oxide; In tetrahydrofuran; water;