Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl-

Base Information

Chemical Name:Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl-
CAS No.:676548-99-5
Molecular Formula:C18H26O3Si
Molecular Weight:318.488
Hs Code.:

Synonyms:

Suppliers and Price of Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl-

There total 5 articles about Silane, [(4S)-4-[(4-methoxyphenyl)methoxy]-5-(2S)-oxiranyl-1-pentynyl]trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 197899-19-7
(2R)-1-chloro-2-hydroxy-4-pentene

: 676548-99-5
[(S)-4-(4-Methoxy-benzyloxy)-5-(S)-oxiranyl-pent-1-ynyl]-trimethyl-silane

Guidance literature:: Multi-step reaction with 6 steps

1.1: 81 percent / KOH

2.1: n-BuLi / tetrahydrofuran / -78 - 20 °C

2.2: BF₃*Et₂O / tetrahydrofuran / 0.33 h / -78 °C

2.3: 75 percent / tetrahydrofuran / 1 h / -78 °C

3.1: 77 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 20 °C

4.1: NaH / dimethylformamide / 0.17 h

4.2: 73 percent / Bu₄NI / dimethylformamide / 25 h / 20 °C

5.1: n-BuLi / tetrahydrofuran / 0.17 h / -50 °C

5.2: 434 mg / tetrahydrofuran / 0.5 h / -40 °C

6.1: 32 percent / (S,S)-salen Co(III)OAc; H₂O / tetrahydrofuran / 1 h

With potassium hydroxide; n-butyllithium; (S,S)-salen Co(III)OAc; water; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja039618+

Reference yield:

: 144422-60-6
(R)-2-but-3-enyloxirane

: 676548-99-5
[(S)-4-(4-Methoxy-benzyloxy)-5-(S)-oxiranyl-pent-1-ynyl]-trimethyl-silane

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-BuLi / tetrahydrofuran / -78 - 20 °C

1.2: BF₃*Et₂O / tetrahydrofuran / 0.33 h / -78 °C

1.3: 75 percent / tetrahydrofuran / 1 h / -78 °C

2.1: 77 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 20 °C

3.1: NaH / dimethylformamide / 0.17 h

3.2: 73 percent / Bu₄NI / dimethylformamide / 25 h / 20 °C

4.1: n-BuLi / tetrahydrofuran / 0.17 h / -50 °C

4.2: 434 mg / tetrahydrofuran / 0.5 h / -40 °C

5.1: 32 percent / (S,S)-salen Co(III)OAc; H₂O / tetrahydrofuran / 1 h

With n-butyllithium; (S,S)-salen Co(III)OAc; water; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja039618+

Reference yield:

: 676548-95-1
(4R)-7-(trimethylsilyl)-1-hepten-6-yne-4-ol

: 676548-99-5
[(S)-4-(4-Methoxy-benzyloxy)-5-(S)-oxiranyl-pent-1-ynyl]-trimethyl-silane

Guidance literature:: Multi-step reaction with 4 steps

1.1: 77 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 20 °C

2.1: NaH / dimethylformamide / 0.17 h

2.2: 73 percent / Bu₄NI / dimethylformamide / 25 h / 20 °C

3.1: n-BuLi / tetrahydrofuran / 0.17 h / -50 °C

3.2: 434 mg / tetrahydrofuran / 0.5 h / -40 °C

4.1: 32 percent / (S,S)-salen Co(III)OAc; H₂O / tetrahydrofuran / 1 h

With n-butyllithium; (S,S)-salen Co(III)OAc; water; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja039618+