4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-

Base Information

Chemical Name:4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-
CAS No.:677007-33-9
Molecular Formula:C26H25N3O2
Molecular Weight:411.503
Hs Code.:
DSSTox Substance ID:DTXSID50477985
Nikkaji Number:J2.040.930D

Synonyms:677007-33-9;1-(2-(1H-Benzo[d]imidazol-2-yl)ethoxy)-2,6-diphenylpiperidin-4-one;4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-;DTXSID50477985

Suppliers and Price of 4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:411.19467705
Heavy Atom Count:31
Complexity:557

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(N(C(CC1=O)C2=CC=CC=C2)OCCC3=NC4=CC=CC=C4N3)C5=CC=CC=C5

Technology Process of 4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl-

There total 4 articles about 4-Piperidinone, 1-[2-(1H-benzimidazol-2-yl)ethoxy]-2,6-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 95-54-5
1,2-diamino-benzene

: 677007-24-8
1-(2-cyanoethoxy)-2,6-diphenylpiperidin-4-one

: 677007-33-9
1-[2-(benzimidazol-2-yl)ethoxy]-2,6-diphenylpiperidin-4-one

Guidance literature:: With hydrogenchloride; In water; for 12h; Heating;
DOI:10.1081/SCC-120028643

Reference yield:

: 10604-77-0
1-hydroxy-2,6-diphenylpiperidin-4-one

: 677007-33-9
1-[2-(benzimidazol-2-yl)ethoxy]-2,6-diphenylpiperidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: resorcinol / Triton B / dioxane / 9 h / 65 - 75 °C

2: aq. HCl / 12 h / Heating

With hydrogenchloride; recorcinol; N-benzyl-trimethylammonium hydroxide; In 1,4-dioxane;
DOI:10.1248/bpb.29.125

Reference yield:

: 5554-55-2,54750-61-7
2,6-diphenyl-4-piperidone

: 677007-33-9
1-[2-(benzimidazol-2-yl)ethoxy]-2,6-diphenylpiperidin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: meta-chloroperbenzoic acid / CHCl₃ / 0 - 20 °C

2: resorcinol / Triton B / dioxane / 9 h / 65 - 75 °C

3: aq. HCl / 12 h / Heating

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; recorcinol; N-benzyl-trimethylammonium hydroxide; In 1,4-dioxane; chloroform;
DOI:10.1248/bpb.29.125