Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-

Base Information

Chemical Name:Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-
CAS No.:145131-46-0
Molecular Formula:C₃₁H₄₄N₄O
Molecular Weight:488.717
Hs Code.:
DSSTox Substance ID:DTXSID00162910
Wikidata:Q83031717
Mol file:145131-46-0.mol

Synonyms:145131-46-0;Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-;C31H44N4O;DTXSID00162910;C31-H44-N4-O;LS-159083

Suppliers and Price of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-

Chemical Property:

Vapor Pressure:2.34E-14mmHg at 25°C
Boiling Point:600°Cat760mmHg
Flash Point:316.7°C
Density:1.09g/cm³
XLogP3:6.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:488.35151204
Heavy Atom Count:36
Complexity:685

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NCC2(CCCC2)C3=CN(C4=CC=CC=C43)CCN(C)C

Technology Process of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)-

There total 3 articles about Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)cyclopentyl)methyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-acetonitrile

: 145131-46-0
1-(2,6-Diisopropyl-phenyl)-3-{1-[1-(2-dimethylamino-ethyl)-1H-indol-3-yl]-cyclopentylmethyl}-urea

Guidance literature:: Multi-step reaction with 3 steps

1: 46 percent / NaH / dimethylsulfoxide; diethyl ether / 4 h / Heating

2: 77 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / Heating

3: K₂CO₃ / dimethylformamide / Heating

With lithium aluminium tetrahydride; sodium hydride; potassium carbonate; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(96)80445-4

Reference yield:

: 176688-86-1
1-[1-(2-Dimethylamino-ethyl)-1H-indol-3-yl]-cyclopentanecarbonitrile

: 145131-46-0
1-(2,6-Diisopropyl-phenyl)-3-{1-[1-(2-dimethylamino-ethyl)-1H-indol-3-yl]-cyclopentylmethyl}-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / Heating

2: K₂CO₃ / dimethylformamide / Heating

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(96)80445-4