Technology Process of Boronic acid, ethyl-, bis(2,2-dimethylpropyl) ester
There total 1 articles about Boronic acid, ethyl-, bis(2,2-dimethylpropyl) ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(R)-Styrene oxide;
With
N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium;
In
hexane; tert-butyl methyl ether;
at -115 ℃;
for 0.166667h;
Inert atmosphere;
Bis(2.2-dimethylpropoxy)(ethyl)boran;
In
tetrahydrofuran; hexane;
at -110 ℃;
for 0.166667h;
Inert atmosphere;
triethylsilyl trifluoromethyl sulfonate;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
stereospecific reaction;
Inert atmosphere;
DOI:10.1021/ol802651b
- Guidance literature:
-
(R)-Styrene oxide;
With
N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium;
In
tetrahydrofuran; hexane;
at -98 ℃;
for 0.166667h;
Inert atmosphere;
Bis(2.2-dimethylpropoxy)(ethyl)boran;
In
tetrahydrofuran; hexane;
at -98 ℃;
for 0.166667h;
Inert atmosphere;
triethylsilyl trifluoromethyl sulfonate;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol802651b
