Benzoic acid, 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)-

Base Information

Chemical Name:Benzoic acid, 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)-
CAS No.:677704-73-3
Molecular Formula:C13H15F3N2O2
Molecular Weight:288.27
Hs Code.:

Synonyms:3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)-benzoic acid;3-(trifluoromethyl)-5-(4-methylpiperazin-1-yl)benzoic acid;3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoic acid;3-(4-methylpiperazin-1-yl)-5-trifluoromethyl-benzoic acid;

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzoic acid, 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)-

Chemical Property:

PSA：43.78000
LogP:2.15830

Purity/Quality:

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Technology Process of Benzoic acid, 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)-

There total 4 articles about Benzoic acid, 3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 677704-72-2
3-(4-methyl-piperazin-1-yl)-5-trifluoromethyl-benzonitrile

: 677704-73-3
3-(4-methylpiperazine-1-yl)-5-(trifluoromethyl)benzoic acid

Guidance literature:: With water; sodium hydroxide; In 1,4-dioxane; Reflux;

Reference yield: 60.0%

: 677704-73-3
3-(4-methylpiperazine-1-yl)-5-(trifluoromethyl)benzoic acid

Guidance literature:: With water; sodium hydroxide; In 1,4-dioxane; Reflux;

Reference yield:

: 677704-68-6
4-(2,4-dimethyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile

: 677704-73-3
3-(4-methylpiperazine-1-yl)-5-(trifluoromethyl)benzoic acid

Guidance literature:: 4-(2,4-dimethyl-1H-imidazol-1-yl)-3-(trifluoromethyl)-benzonitrile; With sodium hydroxide; In 1,4-dioxane; water; at 95 ℃; for 16h;

With hydrogenchloride; In water; pH=~ 5 - 6;