6-(Benzylcarbamoyl)pyridine-2-carboxylic acid

Base Information

Chemical Name:6-(Benzylcarbamoyl)pyridine-2-carboxylic acid
CAS No.:679398-19-7
Molecular Formula:C₁₄H₁₂N₂O₃
Molecular Weight:256.261
Hs Code.:
DSSTox Substance ID:DTXSID90656176
Nikkaji Number:J2.016.976A
Wikidata:Q82570708
ChEMBL ID:CHEMBL4065652

Synonyms:6-(Benzylcarbamoyl)pyridine-2-carboxylic acid;679398-19-7;2-Pyridinecarboxylic acid, 6-[[(phenylmethyl)amino]carbonyl]-;CHEMBL4065652;SCHEMBL10077694;DTXSID90656176;6-[(Benzylamino)carbonyl]-2-pyridinecarboxylic acid;A1-14790;6-[(benzylamino) carbonyl]-2-pyridine carboxylic acid

Suppliers and Price of 6-(Benzylcarbamoyl)pyridine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-(Benzylcarbamoyl)pyridine-2-carboxylic acid

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:256.08479225
Heavy Atom Count:19
Complexity:327

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC(=O)C2=NC(=CC=C2)C(=O)O

Technology Process of 6-(Benzylcarbamoyl)pyridine-2-carboxylic acid

There total 6 articles about 6-(Benzylcarbamoyl)pyridine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₁₄N₂O₃

: 679398-19-7
6-[(benzylamino)carbonyl]-2-pyridine carboxylic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/acs.jmedchem.7b00407

Reference yield:

: 499-83-2
Pyridine-2,6-dicarboxylic acid

: 679398-19-7
6-[(benzylamino)carbonyl]-2-pyridine carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / SOCl₂

2: benzene / 6 h / 50 °C

3: aq. NaOH / 2 h / 40 °C / pH 10

With sodium hydroxide; thionyl chloride; In benzene;
DOI:10.1016/j.cplett.2003.12.093