Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-

Base Information

Chemical Name:Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-
CAS No.:76167-70-9
Molecular Formula:C₁₆H₁₉ClN₄
Molecular Weight:302.807
Hs Code.:
DSSTox Substance ID:DTXSID30227021
Nikkaji Number:J70.355I
Wikidata:Q83106627

Synonyms:2-((1-(p-Chlorobenzyl)-4-piperidyl)amino)pyrimidine;Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-;76167-70-9;DTXSID30227021;LS-134900;N-[1-(p-Chlorobenzyl)-4-piperidyl]-2-pyrimidinamine

Suppliers and Price of Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-

Chemical Property:

Vapor Pressure:2.09E-08mmHg at 25°C
Boiling Point:453.3°Cat760mmHg
Flash Point:228°C
Density:1.266g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:302.1298243
Heavy Atom Count:21
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1NC2=NC=CC=N2)CC3=CC=C(C=C3)Cl

Technology Process of Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)-

There total 2 articles about Pyrimidine, 2-((1-(p-chlorobenzyl)-4-piperidyl)amino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1722-12-9,1195939-87-7
2-chloropyrimidine

: 78471-44-0
1-(4-chloro-benzyl)-piperidin-4-ylamine

: 76167-70-9
[1-(4-Chloro-benzyl)-piperidin-4-yl]-pyrimidin-2-yl-amine

Guidance literature:: With potassium carbonate; In xylene; for 24h; Heating;

Reference yield:

: 68726-76-1
1-(p-chlorobenzyl)-4-piperidone oxime

: 76167-70-9
[1-(4-Chloro-benzyl)-piperidin-4-yl]-pyrimidin-2-yl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / LiAlH₄ / diethyl ether; tetrahydrofuran / 19 h / Heating

2: 45 percent / K₂CO₃ / xylene / 24 h / Heating

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; diethyl ether; xylene;