Technology Process of 1,3-Butanediol, 2-[2-[(1S,2S)-2-hydroxy-2,6,6-trimethylcyclohexyl]ethyl]-,
1-(4-methylbenzenesulfonate)
There total 6 articles about 1,3-Butanediol, 2-[2-[(1S,2S)-2-hydroxy-2,6,6-trimethylcyclohexyl]ethyl]-,
1-(4-methylbenzenesulfonate) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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60134-39-6
(-)-(4aS,8aS)-3,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethylnaphthalen-1(2H)-one
- Guidance literature:
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Multi-step reaction with 6 steps
1: 93 percent / m-chloroperoxybenzoic acid; NaHCO3 / CH2Cl2 / 1.5 h / 20 °C
2: sodium hydroxide / ethanol; H2O / 2.3 h / 20 °C
3: 97 mg / diethyl ether / 0 °C
4: 74 percent / lithium diisopropylamide; hexamethylphosphoramide / tetrahydrofuran / 2.5 h / -78 °C
5: 97 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 °C
6: 62 percent / triethylamine / CH2Cl2 / 13 h / 20 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; lithium aluminium tetrahydride; sodium hydrogencarbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
1: Baeyer-Villiger reaction / 4: aldol condensation;
DOI:10.1081/SCC-120027252
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydroxide / ethanol; H2O / 2.3 h / 20 °C
2: 97 mg / diethyl ether / 0 °C
3: 74 percent / lithium diisopropylamide; hexamethylphosphoramide / tetrahydrofuran / 2.5 h / -78 °C
4: 97 percent / lithium aluminum hydride / diethyl ether / 2 h / 0 °C
5: 62 percent / triethylamine / CH2Cl2 / 13 h / 20 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; lithium aluminium tetrahydride; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
3: aldol condensation;
DOI:10.1081/SCC-120027252