3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole

Base Information

Chemical Name:3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole
CAS No.:680611-20-5
Molecular Formula:C16H13F3N2O
Molecular Weight:306.287
Hs Code.:
DSSTox Substance ID:DTXSID901185913

Synonyms:3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole;680611-20-5;SCHEMBL1407566;DTXSID901185913;3-(4-methoxy-2-methylphenyl)-7-(trifluoro-methyl)-1H-indazole

Suppliers and Price of 3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:306.09799753
Heavy Atom Count:22
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)OC)C2=C3C=CC=C(C3=NN2)C(F)(F)F

Technology Process of 3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole

There total 2 articles about 3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 680610-67-7
[2-fluoro-3-(trifluoromethyl)phenyl]-(4-methoxy-2-methylphenyl)methanone

: 680611-20-5
3-(4-METHOXY-2-METHYLPHENYL)-7-(TRIFLUOROMETHYL)-1H-INDAZOLE

Guidance literature:: With pyridine; dmap; hydrazine hydrate; at 100 ℃;
DOI:10.1021/jm049194+

Reference yield:

: 680611-20-5
3-(4-METHOXY-2-METHYLPHENYL)-7-(TRIFLUOROMETHYL)-1H-INDAZOLE

Guidance literature:

Reference yield:

: 680611-20-5
3-(4-METHOXY-2-METHYLPHENYL)-7-(TRIFLUOROMETHYL)-1H-INDAZOLE

: 4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl]-3-methylphenol

: 4-(2-isopropyl-7-trifluoromethyl-2H-indazol-3-yl)-3-methyl-phenol

Guidance literature:: 3-(4-METHOXY-2-METHYLPHENYL)-7-(TRIFLUOROMETHYL)-1H-INDAZOLE; With sodium hydride; In N,N-dimethyl-formamide;

isopropyl halide; In N,N-dimethyl-formamide; at 60 ℃;

With boron tribromide; In dichloromethane; cyclohexane; at 20 ℃; for 5h;
DOI:10.1021/jm049194+