3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one

Base Information

Chemical Name:3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one
CAS No.:73283-09-7
Molecular Formula:C22H17N3O2
Molecular Weight:355.3893
Hs Code.:

Synonyms:2-(2-Oxo-2-(2-pyridyl)ethyl)-3-o-tolyl-4-(3H)-quinazolinone;4(3H)-Quinazolinone,3-(2-methylphenyl)-2-(2-oxo-2-(2-pyridinyl)ethyl);3-(2-Methylphenyl)-2-(2-oxo-2-(2-pyridinyl)ethyl)-4(3H)-quinazolinone;3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one;

Suppliers and Price of 3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one

Chemical Property:

Vapor Pressure:1.42E-12mmHg at 25°C
Melting Point:254-255 °C
Boiling Point:560°Cat760mmHg
PKA:2.49±0.10(Predicted)
Flash Point:292.5°C
PSA：64.85000
Density:1.24g/cm³
LogP:3.51450

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one

There total 3 articles about 3-(2-methylphenyl)-2-[2-oxo-2-(pyridin-2-yl)ethyl]quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 72-44-6
methaqualone

: 73283-09-7
2-[2-Oxo-2-(2-pyridyl)ethyl]-3-o-tolyl-4-(3H)-quinazolinone

Guidance literature:: With sodium hydride; In 1,2-dimethoxyethane; Heating;
DOI:10.1021/jm00163a027

Reference yield:

: 95-53-4
o-toluidine

: 73283-09-7
2-[2-Oxo-2-(2-pyridyl)ethyl]-3-o-tolyl-4-(3H)-quinazolinone

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / PCl₃ / toluene / 3 h / Heating

2: 80 percent / NaH / 1,2-dimethoxy-ethane / Heating

With sodium hydride; phosphorus trichloride; In 1,2-dimethoxyethane; toluene;
DOI:10.1021/jm00163a027