Chemical Property of 6-methoxy-N-(3-sulfopropyl)quinolinium
Chemical Property:
- Melting Point:299°C dec.
- PSA:78.69000
- LogP:2.15200
- Storage Temp.:-20°C Freezer
- Solubility.:Soluble in water, dimethyl sulfoxide
- XLogP3:1.4
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:4
- Exact Mass:281.07217913
- Heavy Atom Count:19
- Complexity:365
- Purity/Quality:
-
97% *data from raw suppliers
6-Methoxy-N-(3-sulfopropyl)quinolinium *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1=CC2=C(C=C1)[N+](=CC=C2)CCCS(=O)(=O)[O-]
- Recent ClinicalTrials:Primaquine Enantiomers in G6PD Deficient Human Volunteers
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Description
SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.
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Uses
SPQ offers a simple and yet powerful method to examine and measure membrane chloride transport mechanisms.