Chemical Property of Dacinostat
Chemical Property:
- Refractive Index:1.692
- PKA:8.81±0.23(Predicted)
- PSA：88.59000
- Density:1.29 g/cm3
- LogP:3.11440
- Solubility.:insoluble in H2O; insoluble in EtOH; ≥17.45 mg/mL in DMSO
- XLogP3:2.6
- Hydrogen Bond Donor Count:4
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:9
- Exact Mass:379.18959167
- Heavy Atom Count:28
- Complexity:505
- Purity/Quality:
-
99%, *data from raw suppliers
Dacinostat *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
Useful:
- Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)C=CC(=O)NO
- Isomeric SMILES:C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)/C=C/C(=O)NO
-
Uses
Dacinostat is an inhibitors of aberrant chromatin accessibility. It is also used in the synthesis of triazole-linked indole and oxindole glycoconjugates as potential anticancer agents that inhibits the proliferation of the growth of cancer cell lines.
