9H-Xanthene-4,5-dicarboxamide, 2,7-bis(1,1-dimethylethyl)-N,N'-bis[(1S)-1-(hydroxymethyl)-2-phenylethyl ]-9,9-dimethyl-

Base Information

• Chemical Name: 9H-Xanthene-4,5-dicarboxamide, 2,7-bis(1,1-dimethylethyl)-N,N'-bis[(1S)-1-(hydroxymethyl)-2-phenylethyl ]-9,9-dimethyl-
• CAS No.: 681858-43-5
• Molecular Formula: C43H52N2O5
• Molecular Weight: 676.896
• Mol file: 681858-43-5.mol

Synonyms:

Chemical Property of 9H-Xanthene-4,5-dicarboxamide, 2,7-bis(1,1-dimethylethyl)-N,N'-bis[(1S)-1-(hydroxymethyl)-2-phenylethyl ]-9,9-dimethyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9H-Xanthene-4,5-dicarboxamide, 2,7-bis(1,1-dimethylethyl)-N,N'-bis[(1S)-1-(hydroxymethyl)-2-phenylethyl ]-9,9-dimethyl-

There total 2 articles about 9H-Xanthene-4,5-dicarboxamide, 2,7-bis(1,1-dimethylethyl)-N,N'-bis[(1S)-1-(hydroxymethyl)-2-phenylethyl ]-9,9-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.3%

L-Phenylalaninol (3182-95-4) + 2,7-di-tert-butyl-9,9-dimethylxanthene-4,5-dicarbonyl dichloride (166034-31-7) → 2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene-4,5-dicarboxylic acid bis-[(1-hydroxymethyl-2-phenyl-ethyl)-amide] (681858-43-5)

Guidance literature:

In chloroform; at 20 ℃; for 3.5h;

DOI:10.1016/j.tet.2007.11.109

Reference yield: 71.0%

L-Phenylalaninol (3182-95-4) + 2,7-di-t-butyl-9,9-dimethyl-4,5-xanthenedicarboxylic acid (130525-39-2) → 2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene-4,5-dicarboxylic acid bis-[(1-hydroxymethyl-2-phenyl-ethyl)-amide] (681858-43-5)

Guidance literature:

2,7-di-t-butyl-9,9-dimethyl-4,5-xanthenedicarboxylic acid; With thionyl chloride; for 3h; Heating;

L-Phenylalaninol; In chloroform; at 0 - 20 ℃; Further stages.;

DOI:10.1016/j.tetlet.2004.01.043

Reference yield: 98.4%

2,7-di-tert-butyl-9,9-dimethyl-9H-xanthene-4,5-dicarboxylic acid bis-[(1-hydroxymethyl-2-phenyl-ethyl)-amide] (681858-43-5) → 4,5-bis[4'-(S)-benzyl-2'-oxazolin-2'-yl]-2,7-di-tert-butyl-9,9-dimethylxanthene

Guidance literature:

With methanesulfonyl chloride; triethylamine; In chloroform; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2004.01.043

upstream raw materials:

L-Phenylalaninol

2,7-di-t-butyl-9,9-dimethyl-4,5-xanthenedicarboxylic acid

2,7-di-tert-butyl-9,9-dimethylxanthene-4,5-dicarbonyl dichloride