5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one

Base Information

Chemical Name:5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one
CAS No.:68195-42-6
Molecular Formula:C₁₇H₁₄N₂O₂
Molecular Weight:278.31
Hs Code.:
DSSTox Substance ID:DTXSID20459192
Wikidata:Q82282880

Synonyms:68195-42-6;CTK1H6186;DTXSID20459192;4-Methyl-6-(4-phenoxyphenyl)pyridazin-3(2H)-one

Suppliers and Price of 5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:278.105527694
Heavy Atom Count:21
Complexity:442

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NNC1=O)C2=CC=C(C=C2)OC3=CC=CC=C3

Technology Process of 5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one

There total 4 articles about 5-methyl-3-(4-phenoxyphenyl)-1H-pyridazin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 845961-36-6
2-Methylene-4-oxo-4-(4-phenoxy-phenyl)-butyric acid methyl ester

: 68195-42-6
4-methyl-6-(4-phenoxy-phenyl)-2H-pyridazin-3-one

Guidance literature:: With sodium acetate; hydrazine hydrate; In methanol; Heating;

Reference yield:

: 58182-60-8
2-methylene-4-oxo-4-(4-phenoxyphenyl)butanoic acid

: 68195-42-6
4-methyl-6-(4-phenoxy-phenyl)-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / potassium carbonate / acetone / Heating

2: 71 percent / hydrazine hydrate; sodium acetate / methanol / Heating

With sodium acetate; potassium carbonate; hydrazine hydrate; In methanol; acetone;

Reference yield:

: 2170-03-8
itaconic acid anhydride

: 68195-42-6
4-methyl-6-(4-phenoxy-phenyl)-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 61 percent / aluminium chloride / nitrobenzene / 6 h / 20 °C

2: 70 percent / potassium carbonate / acetone / Heating

3: 71 percent / hydrazine hydrate; sodium acetate / methanol / Heating

With aluminium trichloride; sodium acetate; potassium carbonate; hydrazine hydrate; In methanol; nitrobenzene; acetone; 1: Friedel-Crafts acylation;