N8-ACETYLSPERMIDINE DIHYDROCHLORIDE

Base Information

• Chemical Name: N8-ACETYLSPERMIDINE DIHYDROCHLORIDE
• CAS No.: 34450-15-2
• Molecular Formula: C₉H₂₁N₃O*2ClH
• Molecular Weight: 260.207
• Mol file: 34450-15-2.mol

Synonyms:Acetamide,N-[4-[(3-aminopropyl)amino]butyl]-, dihydrochloride (6CI,9CI); N8-Acetylspermidinedihydrochloride

Chemical Property of N8-ACETYLSPERMIDINE DIHYDROCHLORIDE

Chemical Property:

• Melting Point: 200-202 °C
• Boiling Point: 383.2°Cat760mmHg
• Flash Point: 185.5°C
• PSA: 70.64000
• Density: 0.957g/cm³
• LogP: 3.37660
• Storage Temp.: 2-8°C
• Solubility.: H2O: 50 mg/mL, clear, nearly colorless

Purity/Quality:

98%Min ^*data from raw suppliers

N8-Acetylspermidine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: N8-Acetylspermidine Dihydrochloride is an analog of Spermidine (S680400); a biogenic polyamine formed from putrescine essential for both normal and neoplastic tissue growth.

Technology Process of N8-ACETYLSPERMIDINE DIHYDROCHLORIDE

There total 3 articles about N8-ACETYLSPERMIDINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

N8-acetyl-n1-phenylmethoxycarbonylspermidine (86563-01-1) → N8-acetylspermidine dihydrochloride (34450-15-2,120205-19-8)

Guidance literature:

With hydrogen;

Reference yield:

N-(4-aminobutyl)acetamide (5699-41-2) → N8-acetylspermidine dihydrochloride (34450-15-2,120205-19-8)

Guidance literature:

Multi-step reaction with 3 steps

1: CH₂Cl₂

2: NaBH₄

3: 70 percent / H₂

With sodium tetrahydroborate; hydrogen; In dichloromethane;

Reference yield:

{3-[(E)-4-Acetylamino-butylimino]-propyl}-carbamic acid benzyl ester (86550-23-4) → N8-acetylspermidine dihydrochloride (34450-15-2,120205-19-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: 70 percent / H₂

With sodium tetrahydroborate; hydrogen;

upstream raw materials:

N⁸-acetyl-n1-phenylmethoxycarbonylspermidine

N-(4-aminobutyl)acetamide

{3-[(E)-4-Acetylamino-butylimino]-propyl}-carbamic acid benzyl ester

Downstream raw materials:

N-(3-aminopropyl)-1,4-diaminobutane

Refernces