Pacrinolol

Base Information

Chemical Name:Pacrinolol
CAS No.:65655-59-6
Molecular Formula:C23H28N2O4
Molecular Weight:396.4794
Hs Code.:
UNII:CHE211JZXQ
DSSTox Substance ID:DTXSID701024357
Nikkaji Number:J20.063H
Wikipedia:Pacrinolol
Wikidata:Q15634004
NCI Thesaurus Code:C90800

Synonyms:3-(4-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-hydroxypropoxy)phenyl)-2-crotonic acid nitrile;HOE 224;pacrinolol

Suppliers and Price of Pacrinolol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PACRINOLOL 95.00%
5MG
$ 496.07

Total 5 raw suppliers

Chemical Property of Pacrinolol

Chemical Property:

Vapor Pressure:1.42E-15mmHg at 25°C
Boiling Point:606.7°Cat760mmHg
Flash Point:320.7°C
PSA：83.74000
Density:1.135g/cm³
LogP:3.59358
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:396.20490738
Heavy Atom Count:29
Complexity:536

Purity/Quality:

99% ^*data from raw suppliers

PACRINOLOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CC#N)C1=CC=C(C=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O
Isomeric SMILES:C/C(=C\C#N)/C1=CC=C(C=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O

Technology Process of Pacrinolol

There total 5 articles about Pacrinolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.3%

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 115795-51-2
(+/-)-3-<4-(2,3-oxidopropoxy)phenyl>-cis-crotonsaurenitril

: 115795-52-3,115795-53-4,115795-55-6,65655-59-6
(-)-p-[3-[(3,4-dimethoxyphenethyl)amino]-2-hydroxypropoxy]-β-methylcinnamonitrile

Guidance literature:: In ethanol; for 1h; Heating;

Reference yield:

: pacrinolol

: 65655-59-6
(-)-3-<4-<3-(3,4-dimethoxyphenylethylamino)-2-hydroxypropoxyphenyl>-cis-crotonsaurenitril>

Guidance literature:: With ammonium hydroxide; In chloroform; water;

Reference yield:

: 19152-55-7
1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone

: 115795-52-3,115795-53-4,115795-55-6,65655-59-6
(-)-p-[3-[(3,4-dimethoxyphenethyl)amino]-2-hydroxypropoxy]-β-methylcinnamonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 76.1 percent / NaH / tetrahydrofuran / 3 h / 20 °C

2: 60.3 percent / ethanol / 1 h / Heating

With sodium hydride; In tetrahydrofuran; ethanol;