Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-

Base Information

Chemical Name:Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-
CAS No.:83408-68-8
Molecular Formula:C₃₄H₂₄ClN₅OS
Molecular Weight:586.116
Hs Code.:

Synonyms:BRN 4618978;Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-;83408-68-8;LS-153481

Suppliers and Price of Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-

Chemical Property:

Vapor Pressure:1.99E-23mmHg at 25°C
Boiling Point:766.8°Cat760mmHg
Flash Point:417.6°C
Density:1.29g/cm³
XLogP3:7.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:585.1390093
Heavy Atom Count:42
Complexity:984

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=NC2=CC=C(C=C2)C3=NC4=CC=CC=C4C(=O)N3C5=CC(=C(C=C5)Cl)NC(=S)NC6=CC=CC=C6

Technology Process of Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl-

There total 7 articles about Thiourea, N-(2-chloro-5-(4-oxo-2-(4-((phenylmethylene)amino)phenyl)-3(4H)-quinazolinyl)phenyl)-N'-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 83408-62-2
3-(3-Amino-4-chloro-phenyl)-2-(4-{[1-phenyl-meth-(E)-ylidene]-amino}-phenyl)-3H-quinazolin-4-one

: 103-72-0
phenyl isothiocyanate

: 83408-68-8
1-{2-Chloro-5-[4-oxo-2-(4-{[1-phenyl-meth-(E)-ylidene]-amino}-phenyl)-4H-quinazolin-3-yl]-phenyl}-3-phenyl-thiourea

Guidance literature:: In benzene; for 4h; Heating;

Reference yield:

: 635-22-3
4-Chloro-3-nitroaniline

: 83408-68-8
1-{2-Chloro-5-[4-oxo-2-(4-{[1-phenyl-meth-(E)-ylidene]-amino}-phenyl)-4H-quinazolin-3-yl]-phenyl}-3-phenyl-thiourea

Guidance literature:: Multi-step reaction with 3 steps

1: 52 percent / 0.25 h / Heating

2: 61 percent / N₂H₄*H₂O / Raney nickel / ethanol / 12 h / Heating

3: 58 percent / benzene / 4 h / Heating

With hydrazine hydrate; nickel; In ethanol; benzene;

Reference yield:

: 77794-66-2
4-{[1-Phenyl-meth-(E)-ylidene]-amino}-benzoyl chloride

: 83408-68-8
1-{2-Chloro-5-[4-oxo-2-(4-{[1-phenyl-meth-(E)-ylidene]-amino}-phenyl)-4H-quinazolin-3-yl]-phenyl}-3-phenyl-thiourea

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / pyridine / 1 h / 10 °C

2: 52 percent / 0.25 h / Heating

3: 61 percent / N₂H₄*H₂O / Raney nickel / ethanol / 12 h / Heating

4: 58 percent / benzene / 4 h / Heating

With pyridine; hydrazine hydrate; nickel; In ethanol; benzene;