4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

Base Information

Chemical Name:4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one
CAS No.:683240-52-0
Molecular Formula:C8H4BrF3N2O
Molecular Weight:281.032
Hs Code.:
DSSTox Substance ID:DTXSID50468919
Wikidata:Q82296418
Mol file:683240-52-0.mol

Synonyms:683240-52-0;4-bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one;4-Bromo-6-(trifluoromethyl)-1,3-dihydro-1,3-benzodiazol-2-one;4-Bromo-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one;4-bromo-6-(trifluoromethyl)-1,3-dihydrobenzimidazol-2-one;SCHEMBL2417841;SCHEMBL6220507;DTXSID50468919;MFCD18089253;AKOS026673770;TS-03545;CS-0210482;4-Bromo-6-trifluoromethyl-1,3-dihydro-benzoimidazol-2-one;4-Bromo-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-on;4-bromo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one

Suppliers and Price of 4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-6-(trifluoromethyl)-1,3-dihydro-1,3-benzodiazol-2-one
500mg
$ 115.00

Matrix Scientific
4-Bromo-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one 97%
1g
$ 524.00

Crysdot
4-Bromo-6-(trifluoromethyl)-1,3-dihydro-1,3-benzodiazol-2-one 95+%
5g
$ 339.00

Crysdot
4-Bromo-6-(trifluoromethyl)-1,3-dihydro-1,3-benzodiazol-2-one 95+%
10g
$ 564.00

Chemcia Scientific
4-Bromo-6-trifluoromethyl-1,3-dihydro-benzoimidazol-2-one 95%
10 G
$ 600.00

Chemcia Scientific
4-Bromo-6-trifluoromethyl-1,3-dihydro-benzoimidazol-2-one 95%
5 G
$ 360.00

Chemcia Scientific
4-Bromo-6-trifluoromethyl-1,3-dihydro-benzoimidazol-2-one 95%
1 G
$ 120.00

Atlantic Research Chemicals
4-Bromo-6-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one 95%
250mgs:
$ 63.62

Total 7 raw suppliers

Chemical Property of 4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

Chemical Property:

PSA：48.91000
LogP:3.04980
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:279.94591
Heavy Atom Count:15
Complexity:284

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-6-(trifluoromethyl)-1,3-dihydro-1,3-benzodiazol-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C2=C1NC(=O)N2)Br)C(F)(F)F

Technology Process of 4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

There total 2 articles about 4-Bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 113170-72-2
3-bromo-5-(trifluoromethyl)benzene-1,2-diamine

: 530-62-1
1,1'-carbonyldiimidazole

: 683240-52-0
4-bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1021/jm060065y

Reference yield:

: 683240-52-0
4-bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

Guidance literature:

Reference yield: 83.0%

: 683240-52-0
4-bromo-6-trifluoromethyl-1,3-dihydrobenzoimidazol-2-one

: 143418-49-9
3,4,5-trifluorophenylboronic acid

: 683241-24-9
6-(trifluoromethyl)-4-(3,4,5-trifluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 120 ℃; for 0.166667h; microwave irradiation;
DOI:10.1021/jm060065y