ETPI HCL

Base Information

• Chemical Name: ETPI HCL
• CAS No.: 163490-78-6
• Molecular Formula: C10H12ClF3N2S
• Molecular Weight: 248.2679
• Hs Code.: 29309099
• Mol file: 163490-78-6.mol

Synonyms:Carbamimidothioicacid, [4-(trifluoromethyl)phenyl]-, ethyl ester, monohydrochloride (9CI);

Chemical Property of ETPI HCL

Chemical Property:

• Appearance/Colour: white to off-white solid
• Vapor Pressure: 0.000281mmHg at 25°C
• Melting Point: 143-147 °C
• Boiling Point: 322.3 °C at 760 mmHg
• Flash Point: 148.8 °C
• PSA: 61.18000
• Density: 1.27 g/cm³
• LogP: 4.77990
• Storage Temp.: 0-6°C

Purity/Quality:

≥98% ^*data from raw suppliers

S-EthylN-[4-Triflurormethyl)phenyl]isothioUrea,Hydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 μM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake. A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine. A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine