1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one

Base Information

Chemical Name:1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one
CAS No.:124886-01-7
Molecular Formula:C₁₂H₁₁N₃O
Molecular Weight:213.239
Hs Code.:
UNII:ALR3F45M10
DSSTox Substance ID:DTXSID40154516
Pharos Ligand ID:QPVJX125HPFF
ChEMBL ID:CHEMBL88583
Mol file:124886-01-7.mol

Synonyms:1,3-dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one;BMY 20844;BMY-20844

Suppliers and Price of 1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1,3-dihydro-7,8-dimethyl-2H-Imidazo[4,5-b]quinolin-2-one 97.00%
5G
$ 6840.00

AccelPharmtech
1,3-dihydro-7,8-dimethyl-2H-Imidazo[4,5-b]quinolin-2-one 97.00%
1G
$ 3960.00

Total 2 raw suppliers

Chemical Property of 1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one

Chemical Property:

Vapor Pressure:0.000928mmHg at 25°C
Boiling Point:303.5°Cat760mmHg
Flash Point:137.3°C
PSA：61.80000
Density:1.277g/cm³
LogP:2.43350
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:213.090211983
Heavy Atom Count:16
Complexity:307

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1,3-dihydro-7,8-dimethyl-2H-Imidazo[4,5-b]quinolin-2-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C2=CC3=C(NC(=O)N3)N=C2C=C1)C

Technology Process of 1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one

There total 4 articles about 1,3-Dihydro-7,8-dimethyl-2H-imidazo(4,5-b)quinolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 109133-80-4
5-[(2,3-dimethyl-6-nitrophenyl)methylene]-2,4-imidazolidinedione

: 124886-01-7
1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: With iodine; sodium carbonate; sodium thiosulfate; palladium on charcoal; In N-methyl-acetamide; methanol; water;

Reference yield: 49.0%

: 5-[(2,3-dimethyl-6-nitrophenyl)methyl]-2,4-imidazolidinedione

: 1,3-Dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one hydrochloride

: 124886-01-7
1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: With hydrogenchloride; iodine; sodium carbonate; sodium thiosulfate; palladium on charcoal; In N-methyl-acetamide; methanol; water;

Reference yield:

: 109133-99-5
5-<(2,3-dimethyl-6-nitrophenyl)methylene>-2,3-imidazolidinedione

: 124886-01-7
1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂ / 10percent Pd/C / dimethylformamide / 18 h / 3102.9 Torr

2: iodine / methanol / 0.25 h / Heating

With hydrogen; iodine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00113a033