2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol

Base Information

Chemical Name:2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol
CAS No.:685841-35-4
Molecular Formula:C20H23N3O
Molecular Weight:321.422
Hs Code.:
DSSTox Substance ID:DTXSID60432368
Wikidata:Q82246435
ChEMBL ID:CHEMBL65231

Synonyms:CHEMBL65231;685841-35-4;2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol;SCHEMBL5237195;SCHEMBL8313723;2-[(4-benzylpiperidin-1-yl)methyl]-3H-benzimidazol-5-ol;DTXSID60432368;NPFKLNZJQFUMPY-UHFFFAOYSA-N;BDBM50143890;2-[(4-Benzylpiperidin-1-yl)methyl]-1H-benzimidazol-5-ol

Suppliers and Price of 2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:321.184112366
Heavy Atom Count:24
Complexity:390

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC1CC2=CC=CC=C2)CC3=NC4=C(N3)C=C(C=C4)O

Technology Process of 2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol

There total 3 articles about 2-(4-Benzyl-piperidin-1-ylmethyl)-3H-benzoimidazol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 685841-33-2
C₂₁H₂₅N₃O

: 685841-35-4
2-(4-benzylpiperidin-1-ylmethyl)benzimidazol-5-ol

Guidance literature:: C₂₁H₂₅N₃O; With water; hydrogen bromide; at 130 ℃; for 3h;

With ammonium hydroxide; In water; at 20 ℃;
DOI:10.1016/j.ejmech.2011.03.013

Reference yield:

: 31252-42-3
4-benzylpyperidine

: 685841-35-4
2-(4-benzylpiperidin-1-ylmethyl)benzimidazol-5-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate / acetonitrile / 15 h / Reflux

2.1: water; hydrogen bromide / 3 h / 130 °C

2.2: 20 °C

With water; hydrogen bromide; sodium carbonate; In acetonitrile;
DOI:10.1016/j.ejmech.2011.03.013

Reference yield:

: 14625-40-2
2-(chloromethyl)-5-methoxy-1H-benzimidazole

: 685841-35-4
2-(4-benzylpiperidin-1-ylmethyl)benzimidazol-5-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium carbonate / acetonitrile / 15 h / Reflux

2.1: water; hydrogen bromide / 3 h / 130 °C

2.2: 20 °C

With water; hydrogen bromide; sodium carbonate; In acetonitrile;
DOI:10.1016/j.ejmech.2011.03.013