erycibelline

Base Information

• Chemical Name: erycibelline
• CAS No.: 107633-95-4
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.186
• Mol file: 107633-95-4.mol

Synonyms:8-Azabicyclo[3.2.1]octane-2,7-diol,[2S-(exo,exo)]-; (-)-Erycibelline; (2S,7R)-2b,7b-Dihydroxynortropane; Erycibelline

Chemical Property of erycibelline

Chemical Property:

• Vapor Pressure: 2.58E-05mmHg at 25°C
• Boiling Point: 320.4°Cat760mmHg
• Flash Point: 177.1°C
• PSA: 52.49000
• Density: 1.267g/cm³
• LogP: -0.43870

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Erycibelline ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of erycibelline

There total 7 articles about erycibelline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H17NO3 (1345989-13-0) → (-)-erycibelline (107633-95-4)

Guidance literature:

Multi-step reaction with 3 steps

1: samarium diiodide; tert-butyl alcohol / tetrahydrofuran / -78 °C / Inert atmosphere

2: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; water / 2 h / 20 °C

3: copper diacetate; iron; acetic acid / 20 °C

With hydrogenchloride; samarium diiodide; palladium 10% on activated carbon; hydrogen; copper diacetate; iron; acetic acid; tert-butyl alcohol; In tetrahydrofuran; methanol; water;

DOI:10.1039/c1ob06244a

Reference yield:

(1S,2S,5R,7R)-7-(benzyloxy)-8-azabicyclo[3.2.1]octane-2,8-diol (1345989-14-1) → (-)-erycibelline (107633-95-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; palladium 10% on activated carbon; hydrogen / methanol; water / 2 h / 20 °C

2: copper diacetate; iron; acetic acid / 20 °C

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; copper diacetate; iron; acetic acid; In methanol; water;

DOI:10.1039/c1ob06244a

Reference yield:

C7H13NO3 (1345989-15-2) → (-)-erycibelline (107633-95-4)

Guidance literature:

With copper diacetate; iron; acetic acid; at 20 ℃;

DOI:10.1039/c1ob06244a

upstream raw materials:

C₁₄H₁₇NO₃

(1S,2S,5R,7R)-7-(benzyloxy)-8-azabicyclo[3.2.1]octane-2,8-diol

C₇H₁₃NO₃

(2R,4R)-1-hydroxy-2-(3,3-dimethoxypropyl)-4-(tert-butyldimethylsilyloxy)pyrrolidine