N,N'-Dithiobis(N-phenylbenzamide)

Base Information

• Chemical Name: N,N'-Dithiobis(N-phenylbenzamide)
• CAS No.: 2527-63-1
• Molecular Formula: C26H20N2O2S2
• Molecular Weight: 456.589
• Hs Code.: 2930909090
• Mol file: 2527-63-1.mol

Synonyms:P295;Bis-(2-phenylcarbamoyl-phenyl)-disulfid;bis[2-(N-phenylcarbamoyl)phenyl] disulfide;2,2'-disulfanediyl-di-benzoic acid dianilide;2.2'-Dithio-dibenzoesaeure-dianilid;2,2'-Dithiobis(N-phenylbenzamide);bis(o-benzamidophenyl) disulfide;2,2'-Disulfandiyl-di-benzoesaeure-dianilid;2,2'-dithio-bis(phenyl)benzamide;2,2'-Dithiobenzanilide;

Chemical Property of N,N'-Dithiobis(N-phenylbenzamide)

Chemical Property:

• Melting Point: 243 °C
• Boiling Point: 511.4°Cat760mmHg
• PKA: 12.71±0.70(Predicted)
• Flash Point: 263.1°C
• PSA: 115.78000
• Density: 1.35g/cm³
• LogP: 7.75860

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-Dithiobis(N-phenylbenzamide)

There total 19 articles about N,N'-Dithiobis(N-phenylbenzamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2,2'-dithiodibenzoic acid dichloride (19602-82-5) + aniline (62-53-3) → 2,2'-dithiobis(N-phenylbenzamide) (2527-63-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.3390/molecules15118214

Reference yield: 60.0%

N-phenyl benzoyl amide (93-98-1,5705-51-1) → 2,2'-dithiobis(N-phenylbenzamide) (2527-63-1)

Guidance literature:

N-phenyl benzoyl amide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h;

With sulfur; In tetrahydrofuran; hexane; for 1h;

With potassium hexacyanoferrate(III); In tetrahydrofuran; Further stages.;

DOI:10.1021/ja070410o

Reference yield: 55.0%

2-mercapto-N-phenylbenzamide (18205-99-7) → 2,2'-dithiobis(N-phenylbenzamide) (2527-63-1) + 2-phenyl-1,2-benzisothiazolin-3-one (2527-03-9)

Guidance literature:

With oxygen; potassium bromide; In 1,4-dioxane; at 80 ℃; for 24h; under 760.051 Torr;

DOI:10.1016/j.tetlet.2017.03.065

upstream raw materials:

3H-1,2-benzodithiol-3-one

aniline

Thiosalicylic acid

2-trichloromethyl-3,1-benzoxathian-4-one

Downstream raw materials:

2-mercapto-N-phenylbenzamide

(2-phenylcarbamoyl-phenylsulfanyl)-acetic acid

benzo[b]thiophen-3-yl acetate

2-phenyl-1,2-benzisothiazolin-3-one