2-Guanidinobenzimidazole

Base Information

Chemical Name:2-Guanidinobenzimidazole
CAS No.:5418-95-1
Deprecated CAS:108940-88-1,111682-91-8,79454-77-6,111682-91-8,79454-77-6
Molecular Formula:C8H9N5
Molecular Weight:175.193
Hs Code.:2933990090
European Community (EC) Number:226-527-8
NSC Number:10548
UNII:FQ07TOI8GZ
DSSTox Substance ID:DTXSID6063858
Nikkaji Number:J217.997K
Wikidata:Q27105394
Metabolomics Workbench ID:67719
Mol file:5418-95-1.mol

Synonyms:2-benzimidazolylguanidine;2-benzimidazolylguanidine dihydrochloride;2-guanidinebenzimidazole;2-guanidino-benzimidazole;benzimidazolyl-2-guanidine

Suppliers and Price of 2-Guanidinobenzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-1H-Benzimidazol-2-ylguanidine
500mg
$ 319.00

TRC
N-1H-Benzimidazol-2-ylguanidine
2.5g
$ 120.00

SynQuest Laboratories
2-Guanidinobenzimiazole
5 g
$ 248.00

SynQuest Laboratories
2-Guanidinobenzimiazole
1 g
$ 77.00

Sigma-Aldrich
2-Guanidinobenzimidazole 95%
5g
$ 38.90

Matrix Scientific
N-1H-Benzimidazol-2-ylguanidine
500mg
$ 315.00

Chemenu
N-1H-Benzimidazol-2-ylguanidine 95%
10g
$ 422.00

American Custom Chemicals Corporation
N-1H-BENZIMIDAZOL-2-YLGUANIDINE HYDRATE 95.00%
0.5G
$ 726.00

Alichem
1-(1H-Benzo[d]imidazol-2-yl)guanidine
10g
$ 478.06

AK Scientific
N-1H-Benzimidazol-2-ylguanidine
5g
$ 91.00

Total 24 raw suppliers

Chemical Property of 2-Guanidinobenzimidazole

Chemical Property:

Appearance/Colour:BROWN-PURPLE FINE CRYSTALLINE POWDER
Vapor Pressure:1.05E-08mmHg at 25°C
Melting Point:242-244 °C
Refractive Index:1.6900 (estimate)
Boiling Point:461.6 °C at 760 mmHg
PKA:13.67±0.30(Predicted)
Flash Point:233 °C
PSA：90.58000
Density:1.56 g/cm³
LogP:1.74130
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Soluble in DMSO (up to 50 mg/ml) or in Water (up to 4 mg/ml with warming)
XLogP3:0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:175.08579531
Heavy Atom Count:13
Complexity:211

Purity/Quality:

99%, ^*data from raw suppliers

N-1H-Benzimidazol-2-ylguanidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=N2)N=C(N)N
Description 2GBI (5418-95-1) is a selective and state-dependent blocker of voltage-gated proton channels (Hv1).1?2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side.2,3? Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease.4
Uses N-1H-Benzimidazol-2-ylguanidine is used as a reagent in the synthesis of novel fused pyrimidines and imidazoles as potential analgesics.

Technology Process of 2-Guanidinobenzimidazole

There total 8 articles about 2-Guanidinobenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%