Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)-

Base Information

Chemical Name:Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)-
CAS No.:688018-11-3
Molecular Formula:C36H47ClF3N7O3
Molecular Weight:718.262
Hs Code.:

Piperidine,
1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo-
4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl]
butyl]-4-(4-methyl-1-piperazinyl)-

Synonyms:

Suppliers and Price of Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)-

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)-

There total 1 articles about Piperidine, 1-[(2S)-2-[[4-amino-3-chloro-5-(trifluoromethyl)phenyl]methyl]-1,4-dioxo- 4-[4-(1,2,4,5-tetrahydro-2-oxo-3H-1,3-benzodiazepin-3-yl)-1-piperidinyl] butyl]-4-(4-methyl-1-piperazinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 291509-61-0
3-(4-piperidinyl)-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one

: 1400765-55-0
(S)-3-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-4-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-4-oxo-butanoic acid

: 688018-11-3
(S)-2-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-1-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-4-[4-(2-oxo-1,2,4,5-tetrahydro-1,3-benozdiazepin-3-yl)-piperidin-1-yl]-butane-1,4-dione

Guidance literature:: 3-(4-piperidinyl)-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one; (S)-3-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-4-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-4-oxo-butanoic acid; With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In DMF (N,N-dimethylformamide); at 20 ℃; for 12h;

With sodium hydrogencarbonate; In water; ethyl acetate;