4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

Base Information

Chemical Name:4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol
CAS No.:145458-98-6
Molecular Formula:C₂₀H₃₀O₂
Molecular Weight:302.457
Hs Code.:
Mol file:145458-98-6.mol

Synonyms:1H-Cyclohept[b]-as-indacene,A-homo-B-norestr-9-ene-3,17-diol deriv.

Suppliers and Price of 4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

Chemical Property:

Vapor Pressure:1.06E-09mmHg at 25°C
Boiling Point:442.8°Cat760mmHg
Flash Point:200.2°C
PSA：40.46000
Density:1.12g/cm³
LogP:3.98120

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol

There total 2 articles about 4a-methylene-17-methyl-A-homo-B,19-dinorandrost-9-ene-3,17-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 917-54-4
methyllithium

: 145459-01-4
3β-acetoxy-6β-methanesulfonyloxy-5-methyl-19-nor-5β-androst-9-en-17-one

: 145458-98-6
4a-methylene-17α-methyl-A-homo-B,19-dinor-5β-androst-9-ene-3β,17-diol

Guidance literature:: In tetrahydrofuran; diethyl ether; for 4h;
DOI:10.1016/0039-128X(92)90101-E

Reference yield:

: 135573-98-7
C₂₉H₃₈O₇S

: 145458-98-6
4a-methylene-17α-methyl-A-homo-B,19-dinor-5β-androst-9-ene-3β,17-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) lithium aluminum hydride, 2.) pyridine, 3.) p-toluenesulfonic acid

2: 63 percent / tetrahydrofuran / 20 h / Heating

With pyridine; lithium aluminium tetrahydride; toluene-4-sulfonic acid; In tetrahydrofuran;
DOI:10.1016/0039-128X(92)90101-E