Zwj9A2AJ2U

Base Information

Chemical Name:Zwj9A2AJ2U
CAS No.:57103-68-1
Molecular Formula:C28H37 Cl N2 O8
Molecular Weight:565.063
Hs Code.:
European Community (EC) Number:680-675-1,950-267-0
UNII:ZWJ9A2AJ2U
Nikkaji Number:J3.549.707B

Synonyms:maytansinol

Suppliers and Price of Zwj9A2AJ2U

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Maytansinol
10mg
$ 460.00

TRC
Maytansinol
100mg
$ 565.00

Medical Isotopes, Inc.
Maytansinol
2.5 mg
$ 650.00

DC Chemicals
Maytansinol(AnsamitocinP-0) >98%
1 g
$ 2500.00

CSNpharm
Maytansinol
10mg
$ 144.00

CSNpharm
Maytansinol
1mg
$ 52.00

Crysdot
Maytansinol 98+%
5mg
$ 50.00

Crysdot
Maytansinol 98+%
25mg
$ 180.00

Crysdot
Maytansinol 98+%
10mg
$ 80.00

Crysdot
Maytansinol 98+%
50mg
$ 315.00

Total 112 raw suppliers

Chemical Property of Zwj9A2AJ2U

Chemical Property:

Vapor Pressure:1.24E-29mmHg at 25°C
Melting Point:205-207℃
Boiling Point:835.8°Cat760mmHg
PKA:9.89±0.70(Predicted)
Flash Point:459.3°C
PSA：130.09000
Density:1.34g/cm³
LogP:3.51050
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:564.2238438
Heavy Atom Count:39
Complexity:993

Purity/Quality:

99%, ^*data from raw suppliers

Maytansinol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)O)C)C)OC)(NC(=O)O2)O
Isomeric SMILES:C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)O)C)\C)OC)(NC(=O)O2)O
Description Maytansinol (Ansamitocin P-0) is an inhibitor of microtubule assembly that induces microtubule disassembly in vitro.
Uses Maytansinol is used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity. References Pillow, T.H., et. al.: J. Med. Chem., 57, 7890 (2014)

Technology Process of Zwj9A2AJ2U

There total 70 articles about Zwj9A2AJ2U which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 75340-67-9
4-deoxymaytansinol

: 57103-68-1,75494-64-3,75520-30-8,75520-31-9,75520-32-0,93221-26-2,109904-94-1
(-)-maytansinol

Guidance literature:: With 2,6-dimethylpyridine; tert.-butylhydroperoxide; bis(acetylacetonate)oxovanadium; In toluene; for 24h; Ambient temperature;
DOI:10.1021/jo960363a