Benzenemethanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, monohydrobromide

Base Information

• Chemical Name: Benzenemethanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, monohydrobromide
• CAS No.: 70375-50-7
• Molecular Formula: C21H17N3S.BrH
• Molecular Weight: 424.364
• Mol file: 70375-50-7.mol

Synonyms:

Chemical Property of Benzenemethanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, monohydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenemethanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, monohydrobromide

There total 1 articles about Benzenemethanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-benzyl-3-(phenyl-phenyliminomethyl)thiourea (65739-30-2) → 5-benzylamino-2,3-diphenyl-[1,2,4]thiadiazolium; bromide (70375-50-7)

Guidance literature:

With pyridine; bromine; In chloroform; for 1h;

DOI:10.1080/713744577

Reference yield: 75.0%

5-benzylamino-2,3-diphenyl-[1,2,4]thiadiazolium; bromide (70375-50-7) + malononitrile (109-77-3) → 4-amino-3-benzyl-5-cyano-2,3-dihydro-2-(N-phenylbenzimidoyl)iminothiazole

Guidance literature:

With triethylamine; In dichloromethane; for 5h;

DOI:10.1080/713744577

Reference yield:

5-benzylamino-2,3-diphenyl-[1,2,4]thiadiazolium; bromide (70375-50-7) → 7-benzyl-6,7-dihydro-2,2,4-tris(methylamino)-6-(N-phenylbenzimidoyl)imino-thiazolo[4,5-d][1,3,2]diaza-λ5-phosphorine

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / Et₃N / CH₂Cl₂ / 5 h

2: PCl₅ / chlorobenzene / 1 h / 100 °C

3: 75 percent / benzene / 10 h / 20 °C

With phosphorus pentachloride; triethylamine; In dichloromethane; chlorobenzene; benzene;

DOI:10.1080/713744577

upstream raw materials:

1-benzyl-3-(phenyl-phenyliminomethyl)thiourea

Downstream raw materials:

N',N'''-diphenyl-N,N''-(2,4-dibenzyl-[1,2,4]thiadiazolidine-3,5-diylidene)-bis-benzamidine